Transcription Factor
| Accessions: | prd-HD (DrosophilaTF 1.1), prd-PD (DrosophilaTF 1.1) |
| Names: | PRD_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] |
| Length: | 613 |
| Pfam Domains: | 27-151 'Paired box' domain 48-87 Homeodomain-like domain 214-270 Homeobox domain 237-267 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MTVTAFAAAMHRPFFNGYSTMQDMNSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGI 60 61 RPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPRIATPEIENRIEEYKRSSPGM 120 121 FSWEIREKLIREGVCDRSTAPSVSAISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCG 180 181 SDVSGGHHNNGKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDI 240 241 YTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVV 300 301 SSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHH 360 361 QFYNPSANTASYIMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESV 420 421 SSAFGQLPPTPNSLSAVVSGAGVTSSSGANSGADPSQSLANASAGSEELSAALKVESVDL 480 481 IAASQSQLYGGWSSMQALRPNAPLSPEDSLNSTSSTSQALDVTAHQMFHPYQHTPQYASY 540 541 PAPGHAHSHHGHPHAPHPHAHPHPQYAGAHPHYPPPSSSAHFMPQNFNAAAFPSPSKVNY 600 601 TTMPPQPFYPSWY |
| Interface Residues: | 40, 72, 73, 75, 77, 78, 94, 97, 100, 142, 143, 144, 145, 147, 148, 151, 211, 213, 214, 215, 216, 217, 255, 256, 258, 259, 262, 263, 266, 267, 269, 270, 364, 366, 368 |
| 3D-footprint Homologues: | 1k78_A, 6pax_A, 1pdn_C, 6fqp_B, 4j19_B, 1ig7_A, 1puf_B, 5zfz_A, 3cmy_A, 2r5y_A, 1fjl_B, 3d1n_M, 2h1k_B, 6a8r_A, 1puf_A, 1nk2_P, 3lnq_A, 2lkx_A, 1jgg_B, 1zq3_P, 6m3d_C, 6es3_K, 7q3o_C, 2ld5_A, 5jlw_D, 3a01_E, 2h8r_B, 4xrs_G, 2hdd_A, 5flv_I, 1au7_A, 3rkq_B, 7psx_B, 5zjt_E, 2hos_A, 5hod_A, 1b72_A, 4cyc_A, 1ic8_B, 3l1p_A, 7xrc_C, 1le8_A, 1e3o_C, 2xsd_C, 1du0_A, 8g87_X, 1o4x_A, 1le8_B, 4qtr_D, 6fqq_E, 1k61_B, 1mnm_C, 4xrm_B, 4o3m_A |
| Binding Motifs: | prd-HD GaTAATyGATTAks prd-PD ksyCGTCACGsTTsAcm |
| Binding Sites: | prd-HD_1 prd-HD_10 prd-HD_11 prd-HD_12 prd-HD_13 prd-HD_14 prd-HD_15 prd-HD_16 prd-HD_17 prd-HD_18 prd-HD_19 prd-HD_2 prd-HD_20 prd-HD_21 prd-HD_22 prd-HD_23 prd-HD_24 prd-HD_25 prd-HD_26 prd-HD_27 prd-HD_28 prd-HD_29 prd-HD_3 prd-HD_30 prd-HD_31 prd-HD_32 prd-HD_33 prd-HD_34 prd-HD_35 prd-HD_4 prd-HD_5 prd-HD_6 prd-HD_7 prd-HD_8 prd-HD_9 |
| Publications: | Wilson D, Sheng G, Lecuit T, Dostatni N, Desplan C. Cooperative dimerization of paired class homeo domains on DNA. Genes & development 7:2120-34 (1993). [Pubmed] Jun S, Desplan C. Cooperative interactions between paired domain and homeodomain. Development (Cambridge, England) 122:2639-50 (1996). [Pubmed] |
| Related annotations: | PaperBLAST |
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