Transcription Factor

Accessions: Q9VLA2 (JASPAR 2024)
Names: GCM2_DROME, Protein glide-2, Transcription factor glial cells missing 2
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9VLA2
Length: 606
Pfam Domains: 81-223 GCM motif protein
Sequence:
(in bold interface residues)
1 MVVINGYSFKTQQLLTQQPDHSQLTQFVQPQSQSTHSVHPGPSPGQQQAGGSMTMPSSST 60
61 GKGKREWDINDAIVPHVPDQEFDEFNEWSDGHVRHIYSLHNEEAKKHISGWAMRNTNNHN 120
121 VNILKKSCLGVLVCSQHCTLPNGSKINLRPAICDKARRKQEGKACPNKSCRGGRLEIKPC 180
181 RGHCGYPVTHFWRHSGNAIFFQAKGVHDHLRPDPKNSSVSKRAFGRVPLAGKSANGSVAK 240
241 KSVIAGLVKQAKQQHSLISKVLKRPAVSNPLAHTALDIYQYNACGKCAGYSHCTCSYLDD 300
301 STTARSHQLSQSSNYGTNSWPLSGSESSAPCETAANVFTVNHQHITYNYPIYHATPAAAT 360
361 AAPSKSPSLPYACSISELAAYQQSSSGNSFAMGVPVHGHTQCQAVAYDSSPQLATPEPEF 420
421 INYSQIKHLGGGGGQEEISCKAEPGPTIKYNATVETQPYVEDNYDYYYSPKAEYEMQQHH 480
481 HQQQQSHQQFGGNQTAGHHYYESSSGYNGVSYFDTGTTTAPGNTATGNGLEVGYGGYYDH 540
541 YTSYEQQMAVAGGFATAGGSTAPTVAAPPGHPPPPPPPPTLTYHHHHHHHLHHPAAATGL 600
601 APSVTH
Interface Residues: 115, 116, 117, 119, 152
3D-footprint Homologues: 1odh_A
Binding Motifs: MA0917.1 ATGCGGGy
Publications: Schreiber J, Enderich J, Wegner M. Structural requirements for DNA binding of GCM proteins. Nucleic Acids Res 26:2337-43 (1998). [Pubmed]
Related annotations: PaperBLAST

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