Transcription Factor

						

			
Accessions: O15156 (JASPAR 2024)

			
Names: hcKrox, Krueppel-related zinc finger protein cKrox, T-helper-inducing POZ/Krueppel-like factor, ZBT7B_HUMAN, Zfp-67, Zinc finger and BTB domain-containing protein 15, Zinc finger and BTB domain-containing protein 7B, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein Th-POK
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 539
Pfam Domains:    24-144 BTB/POZ domain
  363-385 Zinc-finger double domain
  374-396 Zinc finger, C2H2 type
  374-396 C2H2-type zinc finger
  389-413 Zinc-finger double domain
  402-424 C2H2-type zinc finger
  416-440 Zinc-finger double domain
  430-450 C2H2-type zinc finger
  430-450 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFK   60
  61 KLFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPA  120
 121 VLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATASGVPNGEDS  180
 181 PPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEEEVAG  240
 241 RVGSSGGSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYPPAYGLAQGGGPPLSP  300
 301 EELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGK  360
 361 LPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNH  420
 421 MHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSTAAAS  480
 481 PAGLDLSNGHLDTFRLSLARFWEQSAPTGPPVSTPGPPDDDEEEGAPTTPQAEGAMESS
Interface Residues: 331, 332, 334, 335, 338, 342, 343, 356, 357, 358, 359, 360, 362, 363, 365, 366, 369, 374, 384, 385, 386, 387, 388, 390, 391, 392, 395, 412, 413, 414, 415, 416, 417, 418, 419, 420, 423, 440, 441, 442, 443, 444, 446, 447, 480, 481, 484, 487
3D-footprint Homologues: 5v3j_F, 2i13_A, 1yuj_A, 3uk3_C, 8cuc_F, 7y3l_A, 7n5w_A, 5kkq_D, 5ei9_F, 5k5i_A, 8ssq_A, 7w1m_H, 5und_A, 2gli_A, 1llm_D, 8ssu_A, 6ml4_A, 4x9j_A, 6blw_A, 8h9h_G, 7eyi_G, 7y3m_I, 6e94_A, 7ysf_A, 6wmi_A, 1tf6_A, 2jpa_A, 1ubd_C, 2kmk_A, 1tf3_A, 6jnm_A, 6u9q_A, 5yel_A, 7txc_E, 5kl3_A, 1g2f_F, 5k5l_F, 1mey_C, 4m9v_C, 2lt7_A, 6a57_A, 2wbs_A, 1f2i_J, 2drp_D, 5yj3_D, 8gn3_A
Binding Motifs: MA0694.1 rCGACCMCCgaa
MA0694.2 CGACCMCCga
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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