Transcription Factor

Accessions: T061532_1.02 (CISBP 1.02), UP00354A (UniPROBE 20160601), Q07351 (JASPAR 2024)
Names: STP4, T061532_1.02;, Not Available, STP4_YEAST
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, UniPROBE 20160601 2, JASPAR 2024 3
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Description: Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
Notes: experiment type:PBM, family:C2H2 ZF
Length: 490
Sequence:
(in bold interface residues)
1 MLVSSSFASSIDSVMSHETMSLRRNPPFIDTPEKMPNPTASPNGTIHHLIDPSLPLLSST 60
61 TSSSRSTLSSTLNSPPPPPLTTSYSSYNSSACQSITSSPTDNTALAHNSKCYFPHSLSPT 120
121 PLSSNSSSHVILPPISSFTNLITVAEREFNGRSNSLHANFTSPVPRTVLDHHRHELTFCN 180
181 PNNTTGFKTITPSPPTQHQSILPTAVDNVPRSKSVSSLPVSGFPPLIVKQQQQQQLNSSS 240
241 SASALPSIHSPLTNEHTSRYSSSLKDSAKITKQRKKKECPICHNFYANLSTHKSTHLTPE 300
301 DRPHKCPICQRGFARNNDLIRHKKRHWKDEFMQIYARESDNNSGADDQDDTARTSANNDS 360
361 DDSNDKLAASSSSEETKLLKKNQLKSLYKIKGAFKCPYNSTLINLDMEVYPHKSRSLYFE 420
421 PINCHQTGVFSRCDTFKNHLKALHFEYPPKTKKEDRGVVPGKCKHCGLQFPNVDVWLNKH 480
481 VGKGCGYSYH
Interface Residues: 260, 262, 263, 266, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 314, 315, 316, 317, 318, 319, 320, 321, 322
3D-footprint Homologues: 7ysf_A, 1g2f_F, 6ml4_A, 1mey_C, 4x9j_A, 2kmk_A, 5ei9_F, 7y3l_A, 3uk3_C, 4m9v_C, 6u9q_A, 5v3j_F, 7eyi_G, 2i13_A, 1llm_D, 7n5w_A, 2jpa_A, 5kl3_A, 8h9h_G, 2drp_D, 6e94_A, 2wbs_A, 8ssq_A, 8ssu_A, 5kkq_D, 7txc_E, 1f2i_J, 7w1m_H
Binding Motifs: UP00354A_1 crmtsGtrCGGCTGAwvmsbm
M0503_1.02 arckCTrgd
MA0397.1 gmTAGCGCa
MA0397.2 TAGCGC
Binding Sites: ACAGCCGT
ACGGCTGA
AGCCGCAC
AGCCGCAT
AGCCGCGC
AGCCGTAC
AGCCGTGC
ATAGCGCC
CACGGCTG
CAGCCGCA
CAGCCGTA
CGCCGCAC
CGCGGCTA
CGGCGCTA
GCGCCGCA
GCGGCTGA
AAGCCGTG
ACGCGGCT
AGCCGTAT
CTAGCGCC
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]

Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.