Transcription Factor
| Accessions: | Ascl2_DBD (HumanTF 1.0) |
| Names: | Achaete-scute homolog 2, Ascl2, ASCL2_MOUSE, ASH-2, mASH-2, mASH2 |
| Organisms: | Mus musculus |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | O35885 |
| Notes: | Ensembl ID: ENSMUSG00000009248; DNA-binding domain sequence; TF family: bHLH; Clone source: Hughes lab. |
| Length: | 86 |
| Pfam Domains: | 17-66 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 RRSGATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPHGGANKKLSKVETLRSAVE 60 61 YIRALQRLLAEHDAVRAALAGGLLTP |
| Interface Residues: | 18, 19, 21, 22, 23, 25, 26 |
| 3D-footprint Homologues: | 2ypa_A, 2ql2_D, 5i50_B, 6od3_F, 2ypa_B, 7z5k_B, 5gnj_I |
| Binding Motifs: | Ascl2_DBD arCAGCTGyy |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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