Transcription Factor
| Accessions: | P43688 (JASPAR 2024) |
| Names: | Homeobox protein NK-2 homolog F, Homeobox protein Nkx-2.6, NKX26_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 289 |
| Pfam Domains: | 124-179 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MLSSPVASTPFSVADILRLECQQKDSKTLSQWELHRNPVKPRYLRMNQESGWFESSDRAQ 60 61 AVPFRCTWETVLEMGSNPVGEPQTPPGTISRLGARNPMTDRGVGNLSGDMRRGGPVSTRT 120 121 RPQRKSRVLFSQAQVLALERRFKQQRYLTAPEREHLASALQLTSTQVKIWFQNRRYKSKS 180 181 QRQDQTLELAGHPLAPRRVAVPVLVLDGKPCLDPDVAAFLGPYKATSPYSCFGGYAGTPY 240 241 DASYASRCTSASAGPGPLTPLASSGFSPGGQSAAPQGHLPATPQGVTAW |
| Interface Residues: | 119, 123, 124, 125, 126, 127, 165, 166, 168, 169, 172, 173, 176, 177, 180 |
| 3D-footprint Homologues: | 3a01_E, 4j19_B, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 1mnm_C, 3d1n_M, 5zfz_A, 1fjl_B, 2h1k_B, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 1zq3_P, 1puf_B, 6es3_K, 2ld5_A, 7q3o_C, 1b72_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 4cyc_A, 7psx_B, 1au7_A, 5flv_I, 5zjt_E, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 5hod_A, 4qtr_D, 1du0_A, 8g87_X, 1k61_B, 3l1p_A, 1o4x_A |
| Binding Motifs: | PH0115.1 trAkCCACTTrAvwtt |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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