Transcription Factor
Accessions: | Q13887 (JASPAR 2024) |
Names: | Basic transcription element-binding protein 2, BTE-binding protein 2, Colon krueppel-like factor, GC-box-binding protein 2, Intestinal-enriched krueppel-like factor, KLF5_HUMAN, Krueppel-like factor 5, Transcription factor BTEB2 |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q13887 |
Length: | 457 |
Pfam Domains: | 373-397 C2H2-type zinc finger 374-397 Zinc finger, C2H2 type 389-411 Zinc-finger double domain 403-427 C2H2-type zinc finger 403-427 Zinc finger, C2H2 type 420-444 Zinc-finger double domain 433-455 C2H2-type zinc finger 433-455 Zinc finger, C2H2 type |
Sequence: (in bold interface residues) | 1 MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQA 60 61 QPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVV 120 121 DQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPP 180 181 APTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMP 240 241 SSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYF 300 301 PPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYN 360 361 RRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDEL 420 421 TRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN |
Interface Residues: | 320, 362, 365, 368, 369, 385, 386, 387, 388, 389, 391, 392, 394, 395, 398, 415, 416, 417, 418, 419, 421, 422, 423, 426, 443, 444, 445, 446, 447, 448, 449, 450, 451, 454 |
3D-footprint Homologues: | 6mup_M, 5v3j_F, 5ei9_F, 7ysf_A, 6ml4_A, 7n5w_A, 3uk3_C, 1tf3_A, 6jnm_A, 8ssq_A, 1tf6_A, 7w1m_H, 2i13_A, 7eyi_G, 6blw_A, 5kkq_D, 8ssu_A, 1ubd_C, 1mey_C, 5kl3_A, 6u9q_A, 2kmk_A, 5und_A, 2gli_A, 1g2f_F, 6wmi_A, 8h9h_G, 2lt7_A, 6e94_A, 7y3m_I, 6a57_A, 2jpa_A, 5k5i_A, 8cuc_F, 7y3l_A, 4m9v_C, 5k5l_F, 4x9j_A, 1llm_D, 2wbs_A, 5yel_A, 8gn3_A, 2drp_D, 1f2i_J, 7txc_E, 5yj3_D |
Binding Motifs: | MA0599.1 gCCMCrCCCh |
Binding Sites: | MA0599.1.1 MA0599.1.10 MA0599.1.11 MA0599.1.12 MA0599.1.13 MA0599.1.14 MA0599.1.15 MA0599.1.16 MA0599.1.17 MA0599.1.18 MA0599.1.19 MA0599.1.2 MA0599.1.20 MA0599.1.3 MA0599.1.4 MA0599.1.5 MA0599.1.6 MA0599.1.7 MA0599.1.8 MA0599.1.9 |
Publications: | Ghaleb A.M, Nandan M.O, Chanchevalap S, Dalton W.B, Hisamuddin I.M, Yang V.W. Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation. Cell research 15:92-6 (2005). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.