Transcription Factor
| Accessions: | RELB_HUMAN (HOCOMOCO 10), Q01201 (JASPAR 2024) |
| Names: | I-Rel, RELB_HUMAN, Transcription factor RelB |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q01201 |
| Length: | 579 |
| Pfam Domains: | 127-295 Rel homology domain (RHD) |
| Sequence: (in bold interface residues) | 1 MLRSGPASGPSVPTGRAMPSRRVARPPAAPELGALGSPDLSSLSLAVSRSTDELEIIDEY 60 61 IKENGFGLDGGQPGPGEGLPRLVSRGAASLSTVTLGPVAPPATPPPWGCPLGRLVSPAPG 120 121 PGPQPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEV 180 181 TACLVWKDWPHRVHPHSLVGKDCTDGICRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIE 240 241 RKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNT 300 301 SELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIV 360 361 FKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGMPDVLG 420 421 ELNSSDPHGIESKRRKKKPAILDHFLPNHGSGPFLPPSALLPDPDFFSGTVSLPGLEPPG 480 481 GPDLLDDGFAYDPTAPTLFTMLDLLPPAPPHASAVVCSGGAGAVVGETPGPEPLTLDSYQ 540 541 APGPGDGGTASLVGSNMFPNHYREAAFGGGLLSPGPEAT |
| Interface Residues: | 136, 139, 141, 142, 144, 145, 147, 148, 149, 236, 237, 240, 241, 296, 297, 298, 327, 335, 355 |
| 3D-footprint Homologues: | 1imh_C, 1nfk_A, 7cli_B, 1a3q_A, 2o61_A, 1gji_A, 2ram_A, 3d1n_M |
| Binding Motifs: | RELB_HUMAN.H10MO.C|M01478 rGGGrmTTTcCm MA1117.1 gaATTCCCCks MA1117.2 ATTCCCC |
| Binding Sites: | MA1117.1.1 MA1117.1.10 MA1117.1.11 MA1117.1.12 MA1117.1.13 MA1117.1.14 MA1117.1.15 MA1117.1.16 MA1117.1.17 MA1117.1.18 MA1117.1.19 MA1117.1.2 MA1117.1.20 MA1117.1.3 MA1117.1.4 MA1117.1.5 MA1117.1.6 MA1117.1.7 MA1117.1.8 MA1117.1.9 MA1117.2.1 / MA1117.2.11 / MA1117.2.4 MA1117.2.10 MA1117.2.12 MA1117.2.13 MA1117.2.14 MA1117.2.15 MA1117.2.16 / MA1117.2.17 / MA1117.2.19 / MA1117.2.2 / MA1117.2.20 / MA1117.2.6 / MA1117.2.9 MA1117.2.18 MA1117.2.3 MA1117.2.5 MA1117.2.7 MA1117.2.8 |
| Publications: | Britanova L. V., Makeev V. J., Kuprash D. V. In vitro selection of optimal RelB/p52 DNA-binding motifs.. Biochem. Biophys. Res. Commun. 365:583-588 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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