Transcription Factor

Accessions: Q9C616 (JASPAR 2024), T02209 (AthalianaCistrome v4_May2016)
Names: KAN2_ARATH, Probable transcription factor KAN2, Protein KANADI 2, AT1G32240, KAN2, T02209;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:G2-like
Length: 388
Pfam Domains: 215-266 Myb-like DNA-binding domain
Sequence:
(in bold interface residues)
1 MELFPAQPDLSLQISPPNSKPSSTWQRRRSTTDQEDHEELDLGFWRRALDSRTSSLVSNS 60
61 TSKTINHPFQDLSLSNISHHQQQQQHHHPQLLPNCNSSNILTSFQFPTQQQQQHLQGFLA 120
121 HDLNTHLRPIRGIPLYHNPPPHHHPHRPPPPCFPFDPSSLIPSSSTSSPALTGNNNSFNT 180
181 SSVSNPNYHNHHHQTLNRARFMPRFPAKRSMRAPRMRWTTTLHARFVHAVELLGGHERAT 240
241 PKSVLELMDVKDLTLAHVKSHLQMYRTVKTTDKAAASSGQSDVYENGSSGDNNSDDWMFD 300
301 MNRKSRDSEELTNPLEKSNGLWTNSSGEARLHGKLIDNVAEIMLPSEKELDGKCSSYERI 360
361 SSEEMSSSSISGTSPFKPNLEFTLGRSH
Interface Residues: 215, 255, 256, 259, 260, 263, 264
3D-footprint Homologues: 6j5b_C, 6qec_A, 7d3t_D
Binding Motifs: M0398 / MA1383.1 wtwagaATATTCTyt
M0396 arrGAATAWtc
MA1383.2 aATATTCTyt
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Related annotations: PaperBLAST

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