Transcription Factor

Accessions: ETS1_MOUSE (HOCOMOCO 10), P27577 (JASPAR 2024)
Names: ETS1_MOUSE, p54, Protein C-ets-1
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 440
Pfam Domains: 54-135 Sterile alpha motif (SAM)/Pointed domain
335-416 Ets-domain
Sequence:
(in bold interface residues)
1 MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQ 60
61 QRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMSGAALCALGKECFLELAPDF 120
121 VGDILWEHLEILQKEDVKPYQVNGANPTYPESCYTSDYFISYGIEHAQCVPPSEFSEPSF 180
181 ITESYQTLHPISSEELLSLKYENDYPSVILQDPLQTDTLQTDYFAIKQEVLTPDNMCLGR 240
241 ASRGKLGGQDSFESVESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDYEDYPAALPNHKP 300
301 KGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDG 360
361 WEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQS 420
421 LLGYTPEELHAMLDVKPDAD
Interface Residues: 332, 387, 388, 390, 391, 392, 394, 395, 409
3D-footprint Homologues: 3zp5_A, 1dux_F, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C
Binding Motifs: MA0098.2 cccaCTTCCTGyyyb
ETS1_MOUSE.H10MO.B|M01081 acmGGAWgt
Binding Sites: MA0098.2.1
MA0098.2.10
MA0098.2.11
MA0098.2.12
MA0098.2.13
MA0098.2.14
MA0098.2.15
MA0098.2.16
MA0098.2.17
MA0098.2.18
MA0098.2.19
MA0098.2.2
MA0098.2.20
MA0098.2.3
MA0098.2.4
MA0098.2.5
MA0098.2.6
MA0098.2.7
MA0098.2.8
MA0098.2.9
Publications: Woods D. B., Ghysdael J., Owen M. J. Identification of nucleotide preferences in DNA sequences recognised specifially by c-Ets-1 protein. Nucleic Acids Res. 20:699-704 (1992). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.