Transcription Factor

Accessions: T015225_1.02 (CISBP 1.02)
Names: Hes5, T015225_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 167
Pfam Domains: 18-71 Helix-loop-helix DNA-binding domain
86-122 Hairy Orange
Sequence:
(in bold interface residues)
1 MAPSTVAVEMLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKAD 60
61 ILEMAVSYLKHSKAFAAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQ 120
121 RPPAPAAPAKEPPAPGAAPQPARSSAKAAAAAVSTSRQPACGLWRPW
Interface Residues: 20, 24, 25, 28, 29
3D-footprint Homologues: 1an4_A, 7f2f_B, 4h10_A, 8osl_P, 4h10_B, 8osl_O, 7xhv_B, 5nj8_C, 7xi3_B, 5v0l_B
Binding Motifs: M0215_1.02 grCaCGtGyc
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.