Transcription Factor
| Accessions: | T120855_1.02 (CISBP 1.02), P21538 (JASPAR 2024) |
| Names: | REB1, T120855_1.02;, DNA-binding protein REB1, QBP, REB1_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Myb/SANT |
| Length: | 810 |
| Pfam Domains: | 475-518 Myb-like DNA-binding domain 478-538 Myb-like DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MPSGHNDKNANQESVEEAVLKYVGVGLDHQNHDPQLHTKDLENKHSKKQNIVESSSDVDV 60 61 NNNDDSNRNEDNNDDSENISALNANESSSNVDHANSNEQHNAVMDWYLRQTAHNQQDDED 120 121 DENNNNTDNGNDSNNHFSQSDIVVDDDDDKNKKDAGVGVDDDHQSMAMAAVAAAYTLSKN 180 181 NNNNNSIANDSNSRKRQHDNGNNHENSQKKRKNNNDDDDRQIGNVDPELTTLGDADDNDT 240 241 NNDVIDRDQLVHKAIIDADSITQHPDFQQYLNTAADTDDNEKLKHIKDHLMRTHGLNHQN 300 301 KNHNDDTDDLSNSTKQYSELQKDSMLDSSLNKSRNYMEVLPKVISQDTQPHQQKSPSHDN 360 361 EAGSVDNSEISQLLQSAATKASSLVSLSSSSATPSTSRSNNSKAFDKAEDAALERFINEY 420 421 EAIERLTRQQVCERIWSSDRPKDNFWNNIYKVLPYRSSSSIYKHMRRKYHIFEQRGKWTA 480 481 EEEQELAKLCAEKEGQWAEIGKTLGRMPEDCRDRWRNYVKCGTNRASNRWSVEEEELLKK 540 541 VISDMLEEAQQQQSQLHPNLLEEEQHLLQDDQNDHRNNDEDDDDTASAAAAAAAAIQEQQ 600 601 QLLQQKQQDDDDAIAAAAAAASSSLGDNKDEDKPHDSLGIQLDDNSQNSMVPAPSATSTH 660 661 SKSLSNTIRRHNNKLRKSLMGNGKLDFKDIINWTIVSERMGGTRSRIQCRYKWNKLVKRE 720 721 AIAKIQTVKDDDMLWIFEKLRDLGITEDSQVDWDELAALKPGMKLNGLELKLCYERMKKK 780 781 VKGYKQKSINEISKELVDYFSSNISMKTEN |
| Interface Residues: | 381, 385, 459, 462, 463, 466, 467, 475, 507, 509, 510, 512, 513, 516, 517, 518 |
| 3D-footprint Homologues: | 5eyb_B, 7c4r_A, 2kdz_A, 6kks_A, 3osg_A, 3zqc_A, 1mse_C |
| Binding Motifs: | M1372_1.02 CGGGTAAc MA0363.1 rTTACCCkg MA0363.2 wtyrTTACCCGgmyw MA0363.3 rTTACCCGg |
| Binding Sites: | MA0363.2.1 MA0363.2.10 / MA0363.2.8 MA0363.2.11 / MA0363.2.9 MA0363.2.10 / MA0363.2.12 MA0363.2.11 / MA0363.2.13 MA0363.2.12 / MA0363.2.14 MA0363.2.13 / MA0363.2.15 MA0363.2.14 / MA0363.2.16 MA0363.2.15 / MA0363.2.17 MA0363.2.16 / MA0363.2.18 MA0363.2.17 / MA0363.2.19 MA0363.2.2 MA0363.2.18 / MA0363.2.20 MA0363.2.3 MA0363.2.3 / MA0363.2.4 MA0363.2.4 / MA0363.2.5 MA0363.2.6 MA0363.2.5 / MA0363.2.7 MA0363.2.6 / MA0363.2.8 MA0363.2.7 / MA0363.2.9 MA0363.2.19 MA0363.2.20 MA0363.3.1 MA0363.3.10 MA0363.3.11 / MA0363.3.5 / MA0363.3.7 MA0363.3.12 MA0363.3.13 MA0363.3.14 MA0363.3.15 MA0363.3.16 MA0363.3.17 MA0363.3.18 MA0363.3.19 / MA0363.3.4 MA0363.3.2 MA0363.3.20 / MA0363.3.8 MA0363.3.3 MA0363.3.6 MA0363.3.9 |
| Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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