Transcription Factor
| Accessions: | T049526_1.02 (CISBP 1.02), Q91X45 (JASPAR 2024) |
| Names: | T049526_1.02;, Zbtb3, ZBTB3_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q91X45 |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 518 |
| Pfam Domains: | 14-121 BTB/POZ domain 433-456 Zinc-finger double domain 446-469 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 60 61 RDLVCIHNEIVTAPAFGLLLDFMYAGQLALRGDTPLEDVLAAASYLHMNDIVKVCKQRLQ 120 121 ARALAEADSTKKEEETNPASLEFLSGSSRGPQPLLASVEPSARWNKEEWKGPATPLPIAH 180 181 PADEPPVSGGADTTQPSMEVDSSHLRAPPPPVADVSVSLASPSSSTETIPVNYFSSGLPG 240 241 VSVEPLTPLDVVPESLRVVEPRDTGGPLQGFYPPAPAPPPAPAPVLSQAPAPVEAELVQV 300 301 KVEAIVISDEEADLSEEQPHRSEGLFPPGGAVYGGQPSQAEAFEEPGATGLEEVGPSDHF 360 361 LPPESHLPYHLLPGPGQYHRGLVTSPLPAPAALHEPLYPPPEYEAAQGSFGNFTEDVPTC 420 421 KTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKPD 480 481 PEASTILGVQPLSGSQTTERHSSGGGGPPKEFALGPKN |
| Interface Residues: | 428, 429, 430, 431, 432, 433, 434, 435, 436, 456, 457, 458, 459, 460, 461, 462, 463, 464, 467, 488, 489, 490, 491, 492, 495, 498 |
| 3D-footprint Homologues: | 8cuc_F, 7y3l_A, 6ml4_A, 7n5w_A, 3uk3_C, 2drp_D, 1f2i_J, 6a57_A, 5k5i_A, 2kmk_A, 2gli_A, 8gn3_A, 1g2f_F, 6blw_A, 5kkq_D, 6u9q_A, 4x9j_A, 1llm_D, 5kl3_A, 1ubd_C, 7ysf_A, 6wmi_A, 5ei9_F, 2jpa_A, 1mey_C, 6jnm_A, 5und_A, 5v3j_F, 4m9v_C, 8h9h_G, 7eyi_G, 8ssu_A, 1tf3_A, 2lt7_A, 1tf6_A, 7y3m_I, 2i13_A, 6e94_A, 8ssq_A, 7w1m_H, 7txc_E, 2wbs_A, 5yj3_D, 5yel_A |
| Binding Motifs: | PB0091.1 rabbsCACTGCAytbsk PB0195.1 caatcACTGgyArwww M0442_1.02 mrtgCAGyg |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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