Transcription Factor

Accessions: P63157 (JASPAR 2024)
Names: Bar-class homeodomain protein MBH2, BarH-like 1 homeobox protein, BarH-related homeobox protein 1, BARH1_MOUSE
Organisms: Mus musculus, Rattus norvegicus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 327
Pfam Domains: 179-235 Homeobox domain
Sequence:
(in bold interface residues)
1 MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLE 60
61 TSTSRPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQP 120
121 AAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRK 180
181 ARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVG 240
241 LELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILI 300
301 HGLQGASEPPPPLPPLPGVLPRAAQPR
Interface Residues: 129, 133, 154, 157, 158, 161, 179, 180, 181, 182, 183, 220, 221, 223, 224, 227, 228, 231, 232, 235, 254
3D-footprint Homologues: 3l1p_A, 5zfz_A, 3d1n_M, 1fjl_B, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1nk2_P, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 1mnm_C, 6es3_K, 2ld5_A, 7q3o_C, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 1au7_A, 7xrc_C, 2xsd_C, 1le8_A, 1e3o_C, 1k61_B, 1o4x_A, 1le8_B, 1du0_A, 4qtr_D
Binding Motifs: MA0877.1 syTAAwtGsy
PH0005.1 aamAAcCAATTArkwc
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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