Transcription Factor
| Accessions: | O95365 (JASPAR 2024) |
| Names: | Factor binding IST protein 1, Factor that binds to inducer of short transcripts protein 1, FBI-1, HIV-1 1st-binding protein 1, Leukemia/lymphoma-related factor, POK erythroid myeloid ontogenic factor, Pokemon, Pokemon 1, POZ and Krueppel erythroid myeloid ontogenic factor, TIP21, TTF-I-interacting peptide 21, ZBT7A_HUMAN, Zinc finger and BTB domain-containing protein 7A, Zinc finger protein 857A |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 584 |
| Pfam Domains: | 24-130 BTB/POZ domain 399-421 Zinc-finger double domain 410-432 C2H2-type zinc finger 410-432 Zinc finger, C2H2 type 425-449 Zinc-finger double domain 438-460 C2H2-type zinc finger 438-460 Zinc finger, C2H2 type 452-476 Zinc-finger double domain 466-487 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFK 60 61 KLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVS 120 121 HVCADLLDRQILAADAGADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMNSLPPAAAAAA 180 181 ASFPWSAFGASDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPAERPPTGDGDEGDSN 240 241 PGLWPERDEDAPTGGLFPPPVAPPAATQNGHYGRGGEEEAASLSEAAPEPGDSPGFLSGA 300 301 AEGEDGDGPDVDGLAASTLLQQMMSSVGRAGAAAGDSDEESRADDKGVMDYYLKYFSGAH 360 361 DGDVYPAWSQKVEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFT 420 421 RQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDH 480 481 LHRHLKKDGCNGVPSRRGRKPRVRGGAPDPSPGATATPGAPAQPSSPDARRNGQEKHFKD 540 541 EDEDEDVASPDGLGRLNVAGAGGGGDSGGGPGAATDGNFTAGLA |
| Interface Residues: | 314, 316, 317, 320, 348, 349, 351, 352, 355, 365, 367, 368, 371, 375, 378, 379, 392, 393, 394, 395, 396, 398, 399, 401, 402, 405, 418, 419, 420, 421, 422, 423, 424, 426, 427, 431, 448, 449, 450, 451, 452, 453, 454, 455, 456, 476, 477, 478, 479, 480, 481, 482, 483, 484, 487, 514 |
| 3D-footprint Homologues: | 5v3j_F, 6wmi_A, 1yuj_A, 7n5w_A, 3uk3_C, 8cuc_F, 7y3l_A, 4x9j_A, 6blw_A, 5kkq_D, 1g2f_F, 5ei9_F, 5k5i_A, 2kmk_A, 8ssq_A, 7w1m_H, 1f2i_J, 5und_A, 8ssu_A, 6ml4_A, 8h9h_G, 7eyi_G, 2i13_A, 7y3m_I, 6e94_A, 7ysf_A, 1tf6_A, 2jpa_A, 1ubd_C, 1hwt_C, 1tf3_A, 6jnm_A, 1mey_C, 6u9q_A, 5yel_A, 7txc_E, 5kl3_A, 2gli_A, 1llm_D, 5k5l_F, 2lt7_A, 6a57_A, 8gn3_A, 2wbs_A, 2drp_D, 5yj3_D, 4m9v_C, 1fiu_B |
| Binding Motifs: | MA0750.1 ggCGACCACCga MA0750.2 rsCCGGAAGtgss MA0750.3 CCGGAAGtg |
| Binding Sites: | MA0750.2.1 MA0750.2.10 MA0750.2.11 MA0750.2.12 MA0750.2.13 MA0750.2.14 MA0750.2.15 MA0750.2.16 MA0750.2.17 MA0750.2.18 MA0750.2.19 MA0750.2.2 MA0750.2.20 MA0750.2.3 MA0750.2.4 MA0750.2.5 MA0750.2.6 MA0750.2.7 MA0750.2.8 MA0750.2.9 MA0750.3.1 / MA0750.3.13 / MA0750.3.7 MA0750.3.11 / MA0750.3.20 MA0750.3.10 MA0750.3.12 MA0750.3.14 MA0750.3.15 MA0750.3.16 / MA0750.3.3 MA0750.3.17 MA0750.3.18 MA0750.3.19 MA0750.3.2 MA0750.3.4 MA0750.3.5 MA0750.3.6 MA0750.3.8 MA0750.3.9 |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Pessler F., Hernandez N. Flexible DNA binding of the BTB/POZ-domain protein FBI-1.. J. Biol. Chem. 278:29327-29335 (2003). [Pubmed] |
| Related annotations: | PaperBLAST |
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