Transcription Factor
Accessions: | O70137 (JASPAR 2024) |
Names: | ALX3_MOUSE, Homeobox protein aristaless-like 3, Proline-rich transcription factor ALX3 |
Organisms: | Mus musculus |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 343 |
Pfam Domains: | 154-210 Homeobox domain |
Sequence: (in bold interface residues) | 1 MDPERCAPFSVGPAAGPYAAAGDEAPGPQGTPDAAPHLHPAPPRGPRLSRFPACGPLEPY 60 61 LPEPAKPPAKYLQDLGPGPVLNGGHFYEGSAEAEEKASKAASFPQLPVDCRGGPRDGPSN 120 121 VQASPGPCLASLSVPLSPGLPDSMELAKTKSKKRRNRTTFSTFQLEELEKVFQKTHYPDV 180 181 YAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKMQEGRNPFTTAYDISVLPRTDSHP 240 241 QLQNSLWPSPGSGSPGGPCLMSPEGIPSPCMSPYSHSHGNVAGFMGVPASPAAHPGIYSI 300 301 HGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKEPPGLLNWTT |
Interface Residues: | 104, 105, 106, 110, 111, 123, 126, 153, 154, 155, 156, 157, 195, 196, 198, 199, 202, 203, 206, 207, 210, 211, 221 |
3D-footprint Homologues: | 1au7_A, 4j19_B, 1fjl_B, 3cmy_A, 2h1k_B, 1ig7_A, 1puf_A, 6a8r_A, 3d1n_M, 1puf_B, 5zfz_A, 1zq3_P, 6m3d_C, 3lnq_A, 1nk2_P, 2lkx_A, 1jgg_B, 2ld5_A, 6es3_K, 7q3o_C, 5flv_I, 1b72_A, 5zjt_E, 5hod_A, 3rkq_B, 2hdd_A, 7psx_B, 5jlw_D, 4cyc_A, 2r5y_A, 4xrs_G, 3l1p_A, 2hos_A, 3a01_E, 1e3o_C, 1le8_A, 4qtr_D, 6wig_A, 1du0_A, 4xrm_B |
Binding Motifs: | PH0001.1 wawayTAATTAryTsav |
Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.