Transcription Factor

Accessions: Q9C8P8 (JASPAR 2024), T05163 (AthalianaCistrome v4_May2016)
Names: AtbHLH80, Basic helix-loop-helix protein 80, BH080_ARATH, bHLH 80, bHLH transcription factor bHLH080, Transcription factor bHLH80, Transcription factor EN 71, AT1G35460, bHLH80, T05163;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:bHLH
Length: 259
Pfam Domains: 193-238 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MQSTHISGGSSGGGGGGGGEVSRSGLSRIRSAPATWIETLLEEDEEEGLKPNLCLTELLT 60
61 GNNNSGGVITSRDDSFEFLSSVEQGLYNHHQGGGFHRQNSSPADFLSGSGSGTDGYFSNF 120
121 GIPANYDYLSTNVDISPTKRSRDMETQFSSQLKEEQMSGGISGMMDMNMDKIFEDSVPCR 180
181 VRAKRGCATHPRSIAERVRRTRISDRIRRLQELVPNMDKQTNTADMLEEAVEYVKALQSQ 240
241 IQELTEQQKRCKCKPKEEQ
Interface Residues: 63, 192, 193, 195, 196, 199, 200
3D-footprint Homologues: 7b5y_B, 1am9_A, 7d8t_A, 6g1l_A, 5t01_B, 5gnj_I, 7f2f_B
Binding Motifs: M0161 / MA1357.1 tGCAAGTkGcw
M0163 wkCmACTTGCa
MA1357.2 tGCAAGTkG
Binding Sites: MA1357.1.1
MA1357.1.10
MA1357.1.11
MA1357.1.12
MA1357.1.13
MA1357.1.14
MA1357.1.15
MA1357.1.16
MA1357.1.17
MA1357.1.18
MA1357.1.19
MA1357.1.2
MA1357.1.20
MA1357.1.3
MA1357.1.4
MA1357.1.5
MA1357.1.6
MA1357.1.7
MA1357.1.8
MA1357.1.9
MA1357.2.1
MA1357.2.10
MA1357.2.11
MA1357.2.12
MA1357.2.13
MA1357.2.14
MA1357.2.15
MA1357.2.16
MA1357.2.17
MA1357.2.18
MA1357.2.19
MA1357.2.2
MA1357.2.20
MA1357.2.3
MA1357.2.4
MA1357.2.5
MA1357.2.6
MA1357.2.7
MA1357.2.8
MA1357.2.9
Publications: Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico J.M, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla J.M, Pauwels L, Witters E, Puga M.I, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R. The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses. The Plant cell 23:701-15 (2011). [Pubmed]
Related annotations: PaperBLAST

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