Transcription Factor
| Accessions: | ZSCAN22 (humanC2H2ZF-ChIP Feb2015), P10073 (JASPAR 2024) |
| Names: | ENSG00000182318, P10073, ZSCAN22, Krueppel-related zinc finger protein 2, Protein HKR2, Zinc finger and SCAN domain-containing protein 22, Zinc finger protein 50, ZSC22_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | humanC2H2ZF-ChIP Feb2015 1, JASPAR 2024 2 1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | TF family: C2H2;SCAN experiment: ChIP-seq/MEME/B1H-RC |
| Length: | 491 |
| Pfam Domains: | 44-134 SCAN domain 269-290 Zinc finger, C2H2 type 269-290 C2H2-type zinc finger 269-291 C2H2-type zinc finger 282-307 Zinc-finger double domain 296-318 Zinc finger, C2H2 type 296-318 C2H2-type zinc finger 296-308 C2H2-type zinc finger 310-335 Zinc-finger double domain 323-344 C2H2-type zinc finger 324-346 Zinc finger, C2H2 type 324-346 C2H2-type zinc finger 338-363 Zinc-finger double domain 351-374 C2H2-type zinc finger 352-374 Zinc finger, C2H2 type 352-374 C2H2-type zinc finger 366-390 Zinc-finger double domain 379-400 C2H2-type zinc finger 380-402 Zinc finger, C2H2 type 380-402 C2H2-type zinc finger 394-418 Zinc-finger double domain 407-428 C2H2-type zinc finger 408-430 Zinc finger, C2H2 type 408-430 C2H2-type zinc finger 423-446 Zinc-finger double domain 436-458 Zinc finger, C2H2 type 436-458 C2H2-type zinc finger 436-456 C2H2-type zinc finger 451-475 Zinc-finger double domain 463-484 C2H2-type zinc finger 464-486 Zinc finger, C2H2 type 464-486 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA 60 61 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA 120 121 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP 180 181 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE 240 241 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE 300 301 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT 360 361 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC 420 421 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM 480 481 VHLRIHITVLQ |
| Interface Residues: | 279, 282, 285, 306, 307, 309, 310, 313, 334, 335, 336, 337, 338, 340, 341, 343, 344, 347, 362, 363, 364, 365, 366, 369, 372, 373, 380, 390, 391, 392, 393, 394, 396, 397, 398, 418, 419, 420, 421, 422, 423, 424, 425, 426, 446, 447, 448, 449, 450, 452, 453, 475, 476, 477, 478, 480, 481, 484, 485 |
| 3D-footprint Homologues: | 8ssq_A, 8ssu_A, 1tf3_A, 7w1m_H, 1tf6_A, 5v3j_F, 7ysf_A, 5yel_A, 1ubd_C, 6jnm_A, 2i13_A, 6blw_A, 5ei9_F, 1mey_C, 6wmi_A, 5und_A, 7eyi_G, 2jpa_A, 8gn3_A, 1llm_D, 5kkq_D, 2wbs_A, 5kl3_A, 1f2i_J, 5yj3_D, 2gli_A, 1g2f_F, 4x9j_A, 2kmk_A, 3uk3_C, 6u9q_A, 7txc_E, 6ml4_A, 4m9v_C, 6e94_A, 7n5w_A, 5k5i_A, 5k5l_F, 8h9h_G, 2lt7_A, 6a57_A, 8cuc_F, 7y3l_A, 2drp_D, 7y3m_I |
| Binding Motifs: | ZSCAN22_ChIP CCTCCtCCmTCwGAC UN0668.1 gtchGAkGGmGGMGGCrg UN0668.2 chGAkGGmGGMGGC |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.