Transcription Factor
| Accessions: | PO3F1_MOUSE (HOCOMOCO 10), P21952 (JASPAR 2024) |
| Names: | Oct-6, Octamer-binding protein 6, Octamer-binding transcription factor 6, OTF-6, PO3F1_MOUSE, POU domain transcription factor SCIP, POU domain, class 3, transcription factor 1 |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 449 |
| Pfam Domains: | 246-319 Pou domain - N-terminal to homeobox domain 338-394 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGA 60 61 GHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAA 120 121 HAGAAWAQGGTAHHLGPAMSPSPGAGGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGG 180 181 AGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVG 240 241 EHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLS 300 301 FKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCP 360 361 KPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGG 420 421 SASPPSAPPPPPPAALHHHHHHTLPGSVQ |
| Interface Residues: | 271, 287, 288, 289, 290, 292, 293, 299, 303, 336, 338, 339, 340, 341, 379, 380, 382, 383, 386, 387, 390, 391, 394 |
| 3D-footprint Homologues: | 3l1p_A, 7u0g_M, 3d1n_M, 2xsd_C, 1e3o_C, 7xrc_C, 1au7_A, 8g87_X, 1o4x_A, 3lnq_A, 1puf_A, 1fjl_B, 5zfz_A, 3cmy_A, 2h1k_B, 1ig7_A, 1jgg_B, 1zq3_P, 2lkx_A, 1nk2_P, 7psx_B, 4xrs_G, 3a01_E, 3rkq_B, 2r5y_A, 5hod_A, 5jlw_D, 2ld5_A, 1le8_A, 7q3o_C, 2hdd_A, 6es3_K, 4cyc_A, 1b72_A, 5flv_I, 5zjt_E, 1du0_A |
| Binding Motifs: | PO3F1_MOUSE.H10MO.C|M01295 vrTkswwATGCaww PH0146.1 rmyTAATTAATTAaktm |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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