Transcription Factor

						

			
Accessions: P55771 (JASPAR 2024)

			
Names: PAX9_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P55771
Length: 341
Pfam Domains:     5-128 'Paired box' domain
    24-64 Homeodomain-like domain
Sequence: 
(in bold interface residues)		   1 MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARY   60
  61 NETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSV  120
 121 SSISRILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVP  180
 181 AIPGSVAMPRTWPSSHSVTDILGIRSITDQVSDSSPYHSPKVEEWSSLGRNNFPAAAPHA  240
 241 VNGLEKGALEQEAKYGQAPNGLPAVGSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGH  300
 301 GWQHAGGTSLSPHNCDIPASLAFKGMQAAREGSHSVTASAL
Interface Residues: 17, 49, 50, 52, 54, 55, 71, 74, 77, 91, 93, 95, 101, 103, 119, 120, 121, 122, 124, 125, 128
3D-footprint Homologues: 6pax_A, 1k78_A, 1pdn_C, 1gcc_A
Binding Motifs: MA0781.1 sGTCACGCwTSAsTGmm
UN0502.1 rCCGGAACyACGCwysAmTk
UN0563.1 sGTCACGChYCATTwv
MA0781.2 sGTCACGCwTSAsTGm
			
Publications: Wolf LV, Yang Y, Wang J, Xie Q, Braunger B, Tamm ER, Zavadil J, Cvekl A. Identification of pax6-dependent gene regulatory networks in the mouse lens. PLoS One : (2009;4(1):e4159.). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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