Transcription Factor

Accessions: P14734 (JASPAR 2024)
Names: FKH_DROME
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 510
Pfam Domains: 102-209 Forkhead N-terminal region
210-305 Fork head domain
449-486 HNF3 C-terminal domain
Sequence:
(in bold interface residues)
1 MQKLYAEPPPSSAPVSMASSGGGGPPSGGGGGGGGGGGGGPPPPSNNNPNPTSNGGSMSP 60
61 LARSAYTMNSMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMN 120
121 GSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGS 180
181 REMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFI 240
241 MDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYL 300
301 RRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKEAG 360
361 GASIAGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMA 420
421 NRCHPSLITDYHSSMHPLKQEPSGYTPSSHPFSINRLLPTESKADIKMYDMSQYAGYNAL 480
481 SPLTNSHAALGQDSYYQSLGYHAPAGTTSL
Interface Residues: 205, 207, 253, 255, 256, 257, 259, 260, 261, 263, 264, 273, 280, 305
3D-footprint Homologues: 7yzb_A, 7vox_H, 2hdc_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 3qrf_G
Binding Motifs: MA0446.1 TGTTTryyyAa
Binding Sites: MA0446.1.1
MA0446.1.10
MA0446.1.11
MA0446.1.12
MA0446.1.13
MA0446.1.14
MA0446.1.15
MA0446.1.16
MA0446.1.17
MA0446.1.18
MA0446.1.19
MA0446.1.2
MA0446.1.20
MA0446.1.3
MA0446.1.4
MA0446.1.5
MA0446.1.6
MA0446.1.7
MA0446.1.8
MA0446.1.9
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.