Transcription Factor

Accessions: ATHB12 (ArabidopsisPBM 20140210), T090235_1.02 (CISBP 1.02), Q9M276 (JASPAR 2024)
Names: ATHB-12, ATHB12, T090235_1.02;, ATB12_ARATH, HD-ZIP protein ATHB-12, Homeobox-leucine zipper protein ATHB-12, Homeodomain transcription factor ATHB-12
Organisms: Arabidopsis thaliana
Libraries: ArabidopsisPBM 20140210 1, CISBP 1.02 2, JASPAR 2024 3
1 Franco-Zorrilla J.M, López-Vidriero I, Carrasco J.L, Godoy M, Vera P, Solano R. DNA-binding specificities of plant transcription factors and their potential to define target genes. Proceedings of the National Academy of Sciences of the United States of America : (2014). [Pubmed]
2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HD (HD-ZIPI), experiment type:PBM, family:Homeodomain
Length: 235
Pfam Domains: 32-83 Homeobox domain
85-128 Homeobox associated leucine zipper
Sequence:
(in bold interface residues)
1 MEEGDFFNCCFSEISSGMTMNKKKMKKSNNQKRFSEEQIKSLELIFESETRLEPRKKVQV 60
61 ARELGLQPRQVAIWFQNKRARWKTKQLEKEYNTLRANYNNLASQFEIMKKEKQSLVSELQ 120
121 RLNEEMQRPKEEKHHECCGDQGLALSSSTESHNGKSEPEGRLDQGSVLCNDGDYNNNIKT 180
181 EYFGFEEETDHELMNIVEKADDSCLTSSENWGGFNSDSLLDQSSSNYPNWWEFWS
Interface Residues: 25, 28, 29, 30, 31, 33, 69, 70, 72, 73, 76, 77, 80, 81, 83, 84, 112
3D-footprint Homologues: 3l1p_A, 3d1n_M, 1nk2_P, 1puf_A, 5zjt_E, 4cyc_A, 5jlw_D, 2ld5_A, 1ig7_A, 7q3o_C, 1le8_A, 3a01_E, 2d5v_B, 7psx_B, 3lnq_A, 1b72_A, 6es3_K, 4xrs_G, 3cmy_A, 2h1k_B, 1jgg_B, 5zfz_A, 3rkq_B, 2lkx_A, 1puf_B, 1du0_A, 5flv_I, 2hdd_A, 8g87_X, 2r5y_A, 1zq3_P, 1fjl_B, 6wig_A, 5hod_A, 6a8r_A, 4qtr_D, 2hos_A, 6m3d_C
Binding Motifs: ATHB12 taaTgATTGg
M0849_1.02 kwwwwwwwwm
MA0950.1 aaTgATTG
Publications: Johannesson H., Wang Y., Engstrom P. DNA-binding and dimerization preferences of Arabidopsis homeodomain-leucine zipper transcription factors in vitro. Plant Mol. Biol. 45:63-73 (2001). [Pubmed]
Related annotations: PaperBLAST

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