Transcription Factor
| Accessions: | P09026 (JASPAR 2024) |
| Names: | Homeobox protein Hox-2.7, Homeobox protein Hox-B3, Homeobox protein MH-23, HXB3_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P09026 |
| Length: | 433 |
| Pfam Domains: | 192-248 Homeobox domain 367-431 Domain of unknown function (DUF4074) |
| Sequence: (in bold interface residues) | 1 MQKATYYDNTAAALFGGYSSYPGSNGFGYDGPPQPPFQAATHLEGDYQRSACSLQSLGNA 60 61 APHAKSKELNGSCMRPGLAPEPLPAPPGSPPPSAAPTSTTSNSNNGGGPSKSGPPKCGAG 120 121 SNSTLTKQIFPWMKESRQTSKLKNSSPGTAEGCGGGGGGGGGGGGGGGGSSGGGGGGGGG 180 181 GDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQ 240 241 NRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYDSPSPPAFGKG 300 301 HQNAYALPSNYQPPLKGCGAPQKYPPTPASEYEPHVLQANGGAYGTPTMQGSPVYVGGGG 360 361 YADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAAPMGPNQHHGPCDPHPTYTDLSSHHAPP 420 421 QGRIQEAPKLTHL |
| Interface Residues: | 183, 192, 193, 194, 195, 233, 234, 236, 237, 240, 241, 244, 245, 248 |
| 3D-footprint Homologues: | 3a01_E, 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 1nk2_P, 1zq3_P, 3lnq_A, 1jgg_B, 2lkx_A, 6m3d_C, 2ld5_A, 7q3o_C, 6es3_K, 2hos_A, 1b72_A, 5zjt_E, 4j19_B, 7psx_B, 5hod_A, 5jlw_D, 3rkq_B, 4xrs_G, 2hdd_A, 1au7_A, 4cyc_A, 2r5y_A, 1puf_B, 5flv_I, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 8g87_X, 1o4x_A, 1du0_A, 4qtr_D, 3d1n_M |
| Binding Motifs: | PH0058.1 wravcTMATKAgykrrw |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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