Transcription Factor

						

			
Accessions: GATA-3 (SMILE-seq 1.0)

			
Names: GATA-3, GATA-binding factor 3, GATA3_MOUSE, Trans-acting T-cell-specific transcription factor GATA-3
Organisms: Mus musculus
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: P23772
Length: 441
Pfam Domains:   262-295 GATA zinc finger
  316-348 GATA zinc finger
Sequence: 
(in bold interface residues)		   1 MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLDHSYMEAQYPLTEEVDVLFNIDGQGNHVP   60
  61 SYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALSSHHTASPWNLSPFSKTS  120
 121 IHHGSPGPLSVYPPASSSSLAAGHSSPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEK  180
 181 ECLKYQVQLPDSMKLETSHSRGSMTTLGGASSSAHHPITTYPPYVPEYSSGLFPPSSLLG  240
 241 GSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLI  300
 301 KPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGI  360
 361 QTRNRKMSSKSKKCKKVHDALEDFPKSSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTP  420
 421 MHPPSGLSFGPHHPSSMVTAM
Interface Residues: 271, 272, 274, 284, 288, 325, 326, 328, 338, 342, 343, 346, 362, 363, 365, 366
3D-footprint Homologues: 3vd6_C, 4hc9_A, 3dfx_B, 1gat_A, 4gat_A, 6cnb_R
Binding Motifs: GATA-3 sTTATC
			
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.