Transcription Factor

						

			
Accessions: Q01851 (JASPAR 2024)

			
Names: Brain-3A, Brain-specific homeobox/POU domain protein 3A, Brn-3A, Homeobox/POU domain protein RDC-1, Oct-T1, PO4F1_HUMAN, POU domain, class 4, transcription factor 1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q01851
Length: 419
Pfam Domains:   262-337 Pou domain - N-terminal to homeobox domain
  356-412 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEA   60
  61 LAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHI  120
 121 SSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGG  180
 181 GLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQV  240
 241 AAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPG  300
 301 VGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRT  360
 361 SIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY
Interface Residues: 286, 287, 305, 306, 307, 308, 310, 311, 317, 321, 348, 356, 357, 358, 359, 360, 397, 398, 400, 401, 404, 405, 408, 409, 412
3D-footprint Homologues: 7u0g_M, 3l1p_A, 3cro_R, 3d1n_M, 1o4x_A, 1e3o_C, 7xrc_C, 1au7_A, 8g87_X, 2xsd_C, 2d5v_B, 6a8r_A, 1puf_A, 3cmy_A, 2h1k_B, 5zfz_A, 1fjl_B, 1ig7_A, 1jgg_B, 2lkx_A, 3lnq_A, 1nk2_P, 1zq3_P, 6es3_K, 7q3o_C, 2ld5_A, 3a01_E, 2r5y_A, 1puf_B, 7psx_B, 5flv_I, 2hdd_A, 1b72_A, 5zjt_E, 3rkq_B, 5hod_A, 5jlw_D, 1le8_A, 1du0_A, 4qtr_D, 4xrs_G
Binding Motifs: MA0790.1 aTgmATwATTaATg
MA0790.2 TgmATwATTaAT
			
Publications: Mao CA, Kiyama T, Pan P, Furuta Y, Hadjantonakis AK, Klein WH. Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development 135:271-80 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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