Transcription Factor

						

			
Accessions: O09113 (JASPAR 2024)

			
Names: OTP_MOUSE
Organisms: Mus musculus, Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 325
Pfam Domains:   105-161 Homeobox domain
  302-321 OAR domain
Sequence: 
(in bold interface residues)		   1 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPG   60
  61 EDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELE  120
 121 RSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPG  180
 181 LPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCS  240
 241 LAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSSPDSS  300
 301 DVWRGTSIASLRRKALEHTVSMSFT
Interface Residues: 105, 106, 107, 108, 110, 146, 147, 149, 150, 153, 154, 157, 158, 161
3D-footprint Homologues: 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1puf_B, 1fjl_B, 3d1n_M, 5zfz_A, 1ig7_A, 4j19_B, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 6m3d_C, 2ld5_A, 7q3o_C, 6es3_K, 3l1p_A, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 5flv_I, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D
Binding Motifs: PH0128.1 cryarTTAATTAAykkg
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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