Transcription Factor

						

			
Accessions: 5d8c_A (3D-footprint 20231221), 5e01_A (3D-footprint 20231221)

			
Names: MerR family regulator protein, Y186_HAEIN, Uncharacterized HTH-type transcriptional regulator HI_0186
Organisms: Haemophilus influenzae, strain ATCC 51907 / DSM 11121 / KW20 / Rd
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P44558
Length: 126
Pfam Domains:      3-68 MerR HTH family regulatory protein
     4-41 MerR family regulatory protein
   47-107 MerR, DNA binding
Sequence: 
(in bold interface residues)		   1 MTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTGM   60
  61 SLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAKAL  120
 121 GSVKAV
Interface Residues: 17, 20, 21, 24, 25, 38, 39
3D-footprint Homologues: 1r8e_A, 7ckq_G, 5c8e_C, 6ldi_G, 2vz4_A, 7tea_B, 5d8c_A, 6xh7_H, 2zhg_A, 7tec_A, 5i44_I, 1r8d_B, 6xl5_H, 4r4e_B, 6jgx_B
Binding Motifs: 5d8c_A CTCTnA
5d8c_AB AGAGnnnnCTCT
5e01_A CTCTnA
5e01_AB AGAGnnnnCTCT
Binding Sites: 5d8c_C
5d8c_D
5e01_C / 5e01_D
			
Publications: Couñago RM, Chen NH, Chang CW, Djoko KY, McEwan AG, Kobe B. Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region 44:6981-93 (Nucleic). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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