Transcription Factor

Accessions: P29776 (JASPAR 2024)
Names: ETS6_DROME
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P29776
Length: 475
Pfam Domains: 60-102 Suppressor of cytokine signalling
142-208 Sterile alpha motif (SAM)/Pointed domain
254-336 Ets-domain
Sequence:
(in bold interface residues)
1 MAILQNSRQSHKQLPIISQTIRSAWCQQRPINAMHQDVRQKSIGSGNETKLEAKETEVPT 60
61 NRRRRRRRCSSSSTSDSSASSYSSTDSDSGSSTSSSSIRSQLPALNLPVPLPLATPTPPA 120
121 VSSPHQAPSPRRNSSDSNRSVSPVEVPVDPHAWTPEDIASWVRWATRKFKLDPEPDIDRF 180
181 PKDAQELCDLSRADFWVCAGSRRGGMLLAQHFAISLYHATGRETSPMLNDDEPNPYQLLN 240
241 AASHRLVAQGSGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKA 300
301 KPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSMLGSY 360
361 NHHAGGAMQLGRHPPPLHHHPQHSHPHHQLGQPHFLHPHHSSPASNSSSLGFPSSSTASS 420
421 QASPGQAPASSSASTSNFTAPFQGGTAGVDPARTSTSSAGNYDQGPVTPTTNAFN
Interface Residues: 307, 308, 310, 311, 312, 314, 315, 329
3D-footprint Homologues: 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4iri_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A
Binding Motifs: MA0916.1 CCGGAArY
Publications: Zhu LJ, Christensen RG, Kazemian M, Hull CJ, Enuameh MS, Basciotta MD, Brasefield JA, Zhu C, Asriyan Y, Lapointe DS, Sinha S, Wolfe SA, Brodsky MH. FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system. Nucleic Acids Res : (2011). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.