Transcription Factor
| Accessions: | T012423_1.02 (CISBP 1.02), Q9LTC7 (JASPAR 2024), T13705 (AthalianaCistrome v4_May2016) |
| Names: | bHLH34, T012423_1.02;, AtbHLH34, Basic helix-loop-helix protein 34, BH034_ARATH, bHLH 34, bHLH transcription factor bHLH034, Transcription factor bHLH34, Transcription factor EN 135, AT3G23210, T13705; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2, AthalianaCistrome v4_May2016 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 3 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | experiment type:PBM, family:bHLH, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq |
| Length: | 320 |
| Pfam Domains: | 166-213 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MYPSIEDDDDLLAALCFDQSNGVEDPYGYMQTNEDNIFQDFGSCGVNLMQPQQEQFDSFN 60 61 GNLEQVCSSFRGGNNGVVYSSSIGSAQLDLAASFSGVLQQETHQVCGFRGQNDDSAVPHL 120 121 QQQQGQVFSGVVEINSSSSVGAVKEEFEEECSGKRRRTGSCSKPGTKACREKLRREKLND 180 181 KFMDLSSVLEPGRTPKTDKSAILDDAIRVVNQLRGEAHELQETNQKLLEEIKSLKADKNE 240 241 LREEKLVLKAEKEKMEQQLKSMVVPSPGFMPSQHPAAFHSHKMAVAYPYGYYPPNMPMWS 300 301 PLPPADRDTSRDLKNLPPVA |
| Interface Residues: | 162, 168, 170, 171, 172, 174, 175, 220 |
| 3D-footprint Homologues: | 4efj_A, 7z5k_B, 5gnj_I, 4h10_A, 4h10_B, 8osl_O, 5eyo_A |
| Binding Motifs: | M0157_1.02 gCACGTGk MA0962.1 gCACGTGk M0166 gtgrwwgrCACGTGycarcwygw M0168 wGrCACGTGyhwkmcacryky MA0962.2 gCACGTG |
| Publications: | Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico J.M, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla J.M, Pauwels L, Witters E, Puga M.I, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R. The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses. The Plant cell 23:701-15 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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