Transcription Factor
| Accessions: | O95076 (JASPAR 2024) |
| Names: | ALX3_HUMAN, Homeobox protein aristaless-like 3, Proline-rich transcription factor ALX3 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O95076 |
| Length: | 343 |
| Pfam Domains: | 154-210 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MDPEHCAPFRVGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPY 60 61 LPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSN 120 121 LQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDV 180 181 YAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHP 240 241 QLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYSI 300 301 HGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT |
| Interface Residues: | 123, 126, 153, 154, 155, 156, 157, 195, 196, 198, 199, 202, 203, 206, 207, 210 |
| 3D-footprint Homologues: | 1au7_A, 4j19_B, 1ig7_A, 1puf_A, 6a8r_A, 3d1n_M, 1puf_B, 5zfz_A, 1fjl_B, 3cmy_A, 2h1k_B, 2lkx_A, 1jgg_B, 1zq3_P, 6m3d_C, 3lnq_A, 1nk2_P, 7q3o_C, 6es3_K, 2ld5_A, 7psx_B, 5hod_A, 3rkq_B, 2hdd_A, 5jlw_D, 4cyc_A, 2r5y_A, 4xrs_G, 3l1p_A, 2hos_A, 3a01_E, 5flv_I, 1b72_A, 5zjt_E, 1e3o_C, 1le8_A, 1du0_A, 4xrm_B, 4qtr_D |
| Binding Motifs: | MA0634.1 yyyAATTArm MA0634.2 yAATTA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.