Transcription Factor
| Accessions: | ZNF416 (humanC2H2ZF-ChIP Feb2015) |
| Names: | ENSG00000083817, Q9BWM5, ZNF416 |
| Organisms: | Homo sapiens |
| Libraries: | humanC2H2ZF-ChIP Feb2015 1 1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] |
| Notes: | TF family: C2H2;KRAB experiment: ChIP-seq/MEME/B1H-RC |
| Length: | 594 |
| Pfam Domains: | 28-66 KRAB box 262-280 Zinc-finger double domain 269-290 C2H2-type zinc finger 270-292 Zinc finger, C2H2 type 270-292 C2H2-type zinc finger 284-308 Zinc-finger double domain 298-320 C2H2-type zinc finger 298-320 Zinc finger, C2H2 type 298-320 C2H2-type zinc finger 313-336 Zinc-finger double domain 325-344 C2H2-type zinc finger 326-348 C2H2-type zinc finger 326-348 Zinc finger, C2H2 type 340-364 Zinc-finger double domain 353-376 C2H2-type zinc finger 354-376 C2H2-type zinc finger 354-376 Zinc finger, C2H2 type 369-392 Zinc-finger double domain 381-392 C2H2-type zinc finger 382-404 C2H2-type zinc finger 382-404 Zinc finger, C2H2 type 396-420 Zinc-finger double domain 409-420 C2H2-type zinc finger 410-432 C2H2-type zinc finger 410-432 Zinc finger, C2H2 type 425-448 Zinc-finger double domain 438-460 C2H2-type zinc finger 438-460 C2H2-type zinc finger 438-460 Zinc finger, C2H2 type 453-475 Zinc-finger double domain 466-488 C2H2-type zinc finger 466-488 C2H2-type zinc finger 466-488 Zinc finger, C2H2 type 481-504 Zinc-finger double domain 494-516 Zinc finger, C2H2 type 494-509 C2H2-type zinc finger 494-516 C2H2-type zinc finger 509-531 Zinc-finger double domain 522-544 C2H2-type zinc finger 522-544 Zinc finger, C2H2 type 522-535 C2H2-type zinc finger 537-561 Zinc-finger double domain 549-572 C2H2-type zinc finger 550-572 C2H2-type zinc finger 550-572 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAAAVLRDSTSVPVTAEAKLMGFTQGCVTFEDVAIYFSQEEWGLLDEAQRLLYRDVMLEN 60 61 FALITALVCWHGMEDEETPEQSVSVEGVPQVRTPEASPSTQKIQSCDMCVPFLTDILHLT 120 121 DLPGQELYLTGACAVFHQDQKHHSAEKPLESDMDKASFVQCCLFHESGMPFTSSEVGKDF 180 181 LAPLGILQPQAIANYEKPNKISKCEEAFHVGISHYKWSQCRRESSHKHTFFHPRVCTGKR 240 241 LYESSKCGKACCCECSLVQLQRVHPGERPYECSECGKSFSQTSHLNDHRRIHTGERPYVC 300 301 GQCGKSFSQRATLIKHHRVHTGERPYECGECGKSFSQSSNLIEHCRIHTGERPYECDECG 360 361 KAFGSKSTLVRHQRTHTGEKPYECGECGKLFRQSFSLVVHQRIHTTARPYECGQCGKSFS 420 421 LKCGLIQHQLIHSGARPFECDECGKSFSQRTTLNKHHKVHTAERPYVCGECGKAFMFKSK 480 481 LVRHQRTHTGERPFECSECGKFFRQSYTLVEHQKIHTGLRPYDCGQCGKSFIQKSSLIQH 540 541 QVVHTGERPYECGKCGKSFTQHSGLILHRKSHTVERPRDSSKCGKPYSPRSNIV |
| Interface Residues: | 253, 255, 259, 270, 280, 281, 282, 283, 284, 286, 287, 288, 289, 290, 293, 308, 309, 310, 311, 312, 313, 314, 315, 316, 319, 336, 337, 338, 339, 340, 342, 343, 364, 365, 366, 367, 368, 370, 371, 374, 393, 394, 395, 396, 398, 399, 421, 422, 423, 424, 425, 427, 448, 449, 450, 451, 452, 454, 455, 461, 475, 477, 479, 480, 483, 487, 504, 505, 506, 507, 508, 511, 532, 533, 535, 536, 538, 539, 561, 563, 564, 567 |
| 3D-footprint Homologues: | 7w1m_H, 2kmk_A, 8cuc_F, 6wmi_A, 5ei9_F, 5kl3_A, 4m9v_C, 2i13_A, 6e94_A, 2jpa_A, 6jnm_A, 2drp_D, 1f2i_J, 8ssq_A, 2gli_A, 1g2f_F, 8ssu_A, 1tf6_A, 6ml4_A, 4x9j_A, 5kkq_D, 6u9q_A, 1mey_C, 6a57_A, 5yel_A, 1tf3_A, 7n5w_A, 5und_A, 5k5l_F, 1llm_D, 6blw_A, 8h9h_G, 7y3l_A, 5v3j_F, 2wbs_A, 7eyi_G, 7y3m_I, 8gn3_A, 2lt7_A, 1ubd_C, 5k5i_A, 7txc_E, 7ysf_A, 5yj3_D, 3uk3_C |
| Binding Motifs: | ZNF416_ChIP GTCAACTTGACTGGGCYA |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.