Transcription Factor
| Accessions: | HXA1_MOUSE (HOCOMOCO 10), P09022 (JASPAR 2024) |
| Names: | Early retinoic acid 1, Homeobox protein Hox-1.6, Homeobox protein Hox-A1, Homeoboxless protein ERA-1-399, Homeotic protein ERA-1-993, HXA1_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 331 |
| Pfam Domains: | 229-282 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MNSFLEYPILGSGDSGTCSARAYPSDHGITTFQSCAVSANSCGGDDRFLVGRGVQISSPH 60 61 HHHHHHHHHHPQTATYQTSGNLGISYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYP 120 121 PCAPAVYSGNLSTPMVQHHHHHQGYAGGTVGSPQYIHHSYGQEQQTLALATYNNSLSPLH 180 181 ASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYVGQPNAVRTNFTTKQLTEL 240 241 EKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGSD 300 301 EKTEESSEKSSPSPSAPSPASSTSDTLTTSH |
| Interface Residues: | 227, 229, 230, 231, 267, 268, 270, 271, 274, 275, 278, 279, 282 |
| 3D-footprint Homologues: | 2lkx_A, 1zq3_P, 6m3d_C, 5flv_I, 2ld5_A, 1fjl_B, 5zjt_E, 3a01_E, 2h1k_B, 7psx_B, 1b72_A, 5hod_A, 3lnq_A, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 2hdd_A, 7q3o_C, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 1jgg_B, 6es3_K, 4xrs_G, 3d1n_M, 2hos_A, 5zfz_A, 4cyc_A, 1nk2_P, 4j19_B, 1au7_A, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1k61_B, 3l1p_A, 1o4x_A, 8g87_X, 4qtr_D, 1mnm_C, 1du0_A |
| Binding Motifs: | HXA1_MOUSE.H10MO.C|M01155 wkGATKGATg PH0045.1 ctrarcTAATTAmyky |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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