Transcription Factor
| Accessions: | ems (DrosophilaTF 1.1), P18488 (JASPAR 2024) |
| Names: | EMS_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 497 |
| Pfam Domains: | 392-448 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MTKMIPPVPTAAAAVMMPTPKQKIGFSIESIVGNDVSTAGGNSTPDLSGPQSPPPGERNV 60 61 PGSPPQTPPATLTLIPGSPPHHLMAPPAHGLPYPHPHAQQQQQQHLQAPHPHPHLSPAQQ 120 121 HVLHQHLLMQHQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSL 180 181 KRERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQ 240 241 PPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYIN 300 301 APPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDS 360 361 YQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAE 420 421 RKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGDEDDDELIDM 480 481 EMDECPSDEEHELDASH |
| Interface Residues: | 389, 391, 392, 393, 394, 395, 433, 434, 436, 437, 440, 441, 444, 445, 448 |
| 3D-footprint Homologues: | 1ig7_A, 3d1n_M, 1nk2_P, 1fjl_B, 5zfz_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 6es3_K, 7q3o_C, 2ld5_A, 1au7_A, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 3l1p_A, 5zjt_E, 3a01_E, 5hod_A, 2hdd_A, 7psx_B, 5jlw_D, 3rkq_B, 2r5y_A, 2xsd_C, 1le8_A, 7xrc_C, 1e3o_C, 1k61_B, 6fqp_B, 1o4x_A, 1le8_B, 1du0_A, 8g87_X, 4qtr_D, 1mnm_C, 1puf_B, 4j19_B |
| Binding Motifs: | MA0219.1 yTAATkR ems AAnTnTAATGACA |
| Binding Sites: | MA0219.1.18 MA0219.1.20 MA0219.1.14 MA0219.1.1 MA0219.1.10 MA0219.1.11 MA0219.1.12 MA0219.1.13 MA0219.1.15 MA0219.1.16 MA0219.1.17 MA0219.1.19 MA0219.1.2 MA0219.1.3 MA0219.1.4 MA0219.1.5 MA0219.1.6 MA0219.1.7 MA0219.1.8 MA0219.1.9 |
| Publications: | Taylor H. S. A regulatory element of the spiracles homeobox gene is composed of three distinct conserved regions that bind regulatory proteins.. Mol. Reprod. Dev. 49:246-253 (1998). [Pubmed] Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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