Transcription Factor

Accessions: 6jbq_F (3D-footprint 20231221)
Names: ECF RNA polymerase sigma-E factor, RPOE_ECOLI, Sigma-24
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0AGB6
Length: 186
Pfam Domains: 6-179 ECF sigma factor
21-88 Sigma-70 region 2
125-176 Sigma-70, region 4
131-176 Sigma-70, region 4
Sequence:
(in bold interface residues)
1 LTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSGDVPDVVQEAFIKAYRALDSF 60
61 RGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIEAENFESGGALKEISNPENLMLS 120
121 EELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIAAIMDCPVGTVRSRIFRAREAIDNK 180
181 VQPLIR
Interface Residues: 52, 56, 60, 61, 63, 64, 67, 68, 69, 71, 72, 73, 76, 80, 152, 165, 167, 168, 171, 172
3D-footprint Homologues: 4lup_A, 2h27_A, 6jhe_A
Binding Motifs: 6jbq_F CGGAACTnnnnnnnnnnnnnAnTGTCnnAnC
Binding Sites: 6jbq_G
6jbq_H
Publications: Fang C, Li L, Shen L, Shi J, Wang S, Feng Y, Zhang Y. Structures and mechanism of transcription initiation by bacterial ECF factors. Nucleic Acids Res 47:7094-7104 (2019). [Pubmed]
Related annotations: PaperBLAST

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