Transcription Factor
| Accessions: | Q9VS55 (JASPAR 2024) |
| Names: | CTCF, GH14774p, Q9VS55_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9VS55 |
| Length: | 818 |
| Pfam Domains: | 294-316 C2H2-type zinc-finger domain 322-344 C2H2-type zinc finger 322-344 Zinc finger, C2H2 type 337-361 Zinc-finger double domain 350-368 C2H2-type zinc finger 365-387 Zinc-finger double domain 394-415 Zinc-finger double domain 407-429 C2H2-type zinc-finger domain 422-445 Zinc-finger double domain 435-457 C2H2-type zinc finger 435-457 Zinc finger, C2H2 type 465-488 Zinc finger, C2H2 type 465-485 C2H2-type zinc finger 536-560 Zinc-finger double domain 550-573 Zinc finger, C2H2 type 550-574 C2H2-type zinc-finger domain 550-573 C2H2-type zinc finger 565-598 Zinc-finger double domain 587-609 Zinc finger, C2H2 type 587-609 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MPRRTKKDEDPEDLQTFLNNFHKEIEGNSDEKVVNTILEAISAEAIDLDENGAEAGGSKP 60 61 MEEAEADLDHAEEAEEEEEDDEDKYFIDDEGNCYIKTTPKKQKELQKKLKQAAAKPGKAT 120 121 RSVVSTATNKSINLRPAKSTPKATTSKPPPEPKAISVRPARAAAAKAKQSAMPPPPALVV 180 181 KVPAPRGRPRKNPVIPKPEPMDLERELEELVDEPDISSMVTELSDYTVDEAAVEAATATL 240 241 TPNEAEVYEFEDNATTEDENADKKDVDFVLSNKEVKLKTASSTSQNSNASGHKYSCPHCP 300 301 YTASKKFLITRHSRSHDVEPSFKCSICERSFRSNVGLQNHINTHMGNKPHKCKLCESAFT 360 361 TSGELVRHTRYKHTKEKPHKCTECTYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMF 420 421 KLKRHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNYCPTTCGRKADL 480 481 RVHIKHMHTSDVPMTCRRCGQQLPDRYQYKLHVKSHEGEKCYSCKLCSYASVTQRHLASH 540 541 MLIHLDEKPFHCDQCPQAFRQRQLLRRHMNLVHNEEYQPPEPREKLHKCPSCPREFTHKG 600 601 NLMRHMETHDDSANAREKRRRLKLGRNVRLQKDGTVITLIKDQYVDMDRDQEENEEDDNP 660 661 ESYDLAEIEPENSEAEDADDDVETIVSDPIRQRIKPAPIIINKQARLAASEKQPMIINQR 720 721 LRSQRGTKTFHIKEEPDNSDFTVEWQGDDGEVMVVELVNGDEEVLVKHEPSANSKISAKN 780 781 CFGFEDDDDYEEYGDGENEVDGASQEFLQLMDMIEQDS |
| Interface Residues: | 305, 307, 308, 311, 322, 332, 333, 334, 335, 336, 338, 339, 360, 361, 362, 363, 364, 367, 368, 369, 371, 372, 389, 390, 391, 392, 393, 395, 396, 397, 398, 399, 402, 417, 418, 419, 420, 421, 422, 423, 424, 425, 445, 446, 447, 448, 449, 451, 452, 456, 476, 477, 478, 479, 482, 485, 505, 506, 507, 508, 511, 517, 531, 533, 535, 536, 539, 543, 546, 547, 560, 561, 562, 563, 564, 565, 567, 597, 598, 600 |
| 3D-footprint Homologues: | 1g2f_F, 7w1m_H, 4x9j_A, 5kl3_A, 2kmk_A, 3uk3_C, 8cuc_F, 7y3l_A, 6wmi_A, 1llm_D, 6ml4_A, 2i13_A, 7y3m_I, 1ubd_C, 6jnm_A, 7n5w_A, 8ssq_A, 2gli_A, 8ssu_A, 5v3j_F, 5kkq_D, 5ei9_F, 7txc_E, 7eyi_G, 8h9h_G, 7ysf_A, 6a57_A, 1tf3_A, 1tf6_A, 5und_A, 1mey_C, 6blw_A, 6u9q_A, 4m9v_C, 2lt7_A, 6e94_A, 2jpa_A, 5k5i_A, 8gn3_A, 2wbs_A, 1f2i_J, 2drp_D, 5yel_A, 5k5l_F, 5yj3_D, 1yuj_A |
| Binding Motifs: | MA0531.1 ccgmyAGrTGGCGCy MA0531.2 yAGrTGGCGC |
| Binding Sites: | MA0531.1.1 MA0531.1.10 MA0531.1.11 MA0531.1.12 MA0531.1.13 MA0531.1.14 MA0531.1.15 MA0531.1.16 MA0531.1.17 MA0531.1.18 MA0531.1.19 MA0531.1.2 MA0531.1.20 MA0531.1.3 MA0531.1.4 MA0531.1.5 MA0531.1.6 MA0531.1.7 MA0531.1.8 MA0531.1.9 MA0531.2.1 MA0531.2.10 MA0531.2.11 MA0531.2.12 MA0531.2.13 MA0531.2.14 MA0531.2.15 MA0531.2.16 MA0531.2.17 MA0531.2.18 MA0531.2.19 MA0531.2.2 MA0531.2.20 MA0531.2.3 MA0531.2.4 MA0531.2.5 MA0531.2.6 MA0531.2.7 MA0531.2.8 MA0531.2.9 |
| Publications: | Holohan E.E, Kwong C, Adryan B, Bartkuhn M, Herold M, Renkawitz R, Russell S, White R. CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex. PLoS genetics 3:e112 (2007). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.