Transcription Factor

Accessions: Q9D030 (JASPAR 2024)
Names: Dermis-expressed protein 1, Dermo-1, Twist-related protein 2, TWST2_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9D030
Length: 160
Pfam Domains: 67-117 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQS 60
61 FEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQV 120
121 LQSDEMDNKMTSCSYVAHERLSYAYSVWRMEGAWSMSASH
Interface Residues: 68, 69, 71, 72, 73, 74, 75, 76, 78, 79, 86, 88, 103
3D-footprint Homologues: 2ypa_A, 1gdt_A, 6od3_F, 5eyo_A, 7z5k_B, 5i50_B, 2ypa_B, 2ql2_A, 2ql2_D, 5gnj_I, 7ssa_L
Binding Motifs: MA0633.1 rmCATATGTk
MA0633.2 vvCAGCTGbb
MA0633.3 CAGCTG
Binding Sites: MA0633.3.1 / MA0633.3.10 / MA0633.3.11 / MA0633.3.12 / MA0633.3.13 / MA0633.3.14 / MA0633.3.15 / MA0633.3.16 / MA0633.3.19 / MA0633.3.2 / MA0633.3.20 / MA0633.3.3 / MA0633.3.4 / MA0633.3.5 / MA0633.3.6 / MA0633.3.7 / MA0633.3.8 / MA0633.3.9
MA0633.2.1 / MA0633.2.9
MA0633.2.10 / MA0633.2.2
MA0633.2.11 / MA0633.2.12
MA0633.2.13
MA0633.2.14
MA0633.2.15
MA0633.2.16
MA0633.2.17
MA0633.2.18
MA0633.2.17 / MA0633.2.19
MA0633.2.18 / MA0633.2.20
MA0633.2.3
MA0633.2.4
MA0633.2.5
MA0633.2.6
MA0633.2.7
MA0633.2.8
MA0633.2.19
MA0633.2.20
MA0633.3.17
MA0633.3.18
Publications: Kophengnavong T, Michnowicz J.E, Blackwell T.K. Establishment of distinct MyoD, E2A, and twist DNA binding specificities by different basic region-DNA conformations. Molecular and cellular biology 20:261-72 (2000). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.