Transcription Factor
Accessions: | P09631 (JASPAR 2024) |
Names: | Homeobox protein Hox-1.7, Homeobox protein Hox-A9, HXA9_MOUSE |
Organisms: | Mus musculus |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 271 |
Pfam Domains: | 1-192 Hox9 activation region 206-262 Homeobox domain |
Sequence: (in bold interface residues) | 1 MATTGALGNYYVDSFLLGADAADELGAGRYAPGTLGQPPRQAAALAEHPDFSPCSFQSKA 60 61 AVFGASWNPVHAAGANAVPAAVYHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSF 120 121 AGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAE 180 181 NESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVAR 240 241 LLNLTERQVKIWFQNRRMKMKKINKDRAKDE |
Interface Residues: | 206, 207, 208, 209, 247, 248, 250, 251, 254, 255, 258, 259, 260, 262 |
3D-footprint Homologues: | 2h1k_B, 5zfz_A, 1puf_A, 1ig7_A, 3cmy_A, 3d1n_M, 6a8r_A, 1fjl_B, 2lkx_A, 1jgg_B, 1nk2_P, 1zq3_P, 3lnq_A, 7q3o_C, 2ld5_A, 6es3_K, 1b72_A, 3rkq_B, 6m3d_C, 5flv_I, 2hdd_A, 5zjt_E, 4cyc_A, 2r5y_A, 1puf_B, 7psx_B, 2hos_A, 5jlw_D, 4xrs_G, 3a01_E, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1au7_A, 1mnm_C, 1du0_A, 5hod_A, 4qtr_D, 1k61_B, 1o4x_A |
Binding Motifs: | MA0594.1 syCATmAATCA PH0056.1 rcggycATwAAAwtadw |
Binding Sites: | MA0594.1.1 MA0594.1.10 MA0594.1.11 MA0594.1.12 MA0594.1.13 MA0594.1.14 MA0594.1.15 MA0594.1.16 MA0594.1.17 MA0594.1.18 MA0594.1.19 MA0594.1.2 MA0594.1.20 MA0594.1.3 MA0594.1.4 MA0594.1.5 MA0594.1.6 MA0594.1.7 MA0594.1.8 MA0594.1.9 |
Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] LaRonde-LeBlanc N.A, Wolberger C. Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior. Genes & development 17:2060-72 (2003). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.