Transcription Factor
| Accessions: | ATF4 (HT-SELEX2 May2017) |
| Names: | ATF4, ENSG00000128272 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bZIP experiment: HT-SELEX Hamming distance: 2 cycle: 3, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 3 |
| Length: | 96 |
| Pfam Domains: | 21-82 bZIP transcription factor 24-75 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 ARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEK 60 61 KNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP |
| Interface Residues: | 33, 34, 36, 37, 40, 41 |
| 3D-footprint Homologues: | 2wt7_A, 6mg1_B |
| Binding Motifs: | ATF4_2 ggaTGACGTCAtcc ATF4_3 rgATGACGTCATcy ATF4_methyl_1 rGATGATGTCATcy |
| Related annotations: | PaperBLAST |
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