Transcription Factor
| Accessions: | T144592_1.02 (CISBP 1.02), Q04886 (JASPAR 2024) |
| Names: | Sox8, T144592_1.02;, SOX8_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Sox |
| Length: | 464 |
| Pfam Domains: | 5-86 Sox developmental protein N terminal 99-167 HMG (high mobility group) box 100-162 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MLDMSEARAQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGGGGRGDTAEAADER 60 61 FPACIRDAVSQVLKGYDWSLVPMPVRGGGGGTLKAKPHVKRPMNAFMVWAQAARRKLADQ 120 121 YPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKTGR 180 181 SDSDSGTELGHHPGGPMYKADAVLGEAHHHSDHHTGQTHGPPTPPTTPKTDLHQASNGSK 240 241 QELRLEGRRLVDSGRQNIDFSNVDISELSSEVISNMDTFDVHEFDQYLPLNGHSALPTEP 300 301 SQATASGSYGGASYSHSGATGIGASPVWAHKGAPSASASPTEAGPLRPQIKTEQLSPSHY 360 361 NDQSHGSPGRADYGSYSAQASVTTAASATAASSFASAQCDYTDLQASNYYSPYPGYPPSL 420 421 YQYPYFHSSRRPYASPLLNGLSMPPAHSPSSNWDQPVYTTLTRP |
| Interface Residues: | 101, 104, 106, 107, 110, 114, 125, 126, 127, 130, 168, 172 |
| 3D-footprint Homologues: | 3u2b_C, 7m5w_A, 2gzk_A, 4s2q_D, 1j5n_A, 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 6jrp_D, 1qrv_A, 1hry_A |
| Binding Motifs: | PB0074.1 kkatywATTGTTmwkwa PB0178.1 acATTCAtgamass M1584_1.02 ATTgwtyy |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.