Transcription Factor

Accessions: Q5ZL67 (JASPAR 2024)
Names: Endoplasmic reticulum membrane sensor NFE2L1, NF-E2-related factor 1, NF2L1_CHICK, NFE2-related factor 1, Nuclear factor erythroid 2-related factor 1, Nuclear factor, erythroid derived 2, like 1
Organisms: Gallus gallus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q5ZL67
Length: 772
Pfam Domains: 656-714 bZIP transcription factor
659-705 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MLSLKKYFTEGLIQFTILLSLIGVRVDVDTYLNSQLPPLREIILGQSSAYTQTQFHNLRN 60
61 TLDGYGIHPKSVDLDYYFTARRLLNQVRALDRFQVPTTEVSAWLVHRDPDGSVSGTQPSA 120
121 GIALENSGGLQDGTGPDGAVRESGAEQGFGEELEDLGAVAAPVNGDLTKEDIDLIDILWR 180
181 QDIDLGAGREIFDYSHRQKESEVDKELSDGRERGDGWRSAGGQVTNRNLLVDGETGESFP 240
241 AQVPGVEDQTALSLEECLRLLEATFPFGENSEFPAADVSTLSEAVPSESRPAGIQSSLLS 300
301 PLLPETESPFDLEQQWQDLMSIMEMQAMEVNNTTAETLYNGTSGDLLTSNYNLAPNTPIN 360
361 QNVSLHQASLGSCSQDFSLFSSEIESPSMGGSSALLQLAPDNSTGLNTTFSSTNFSGIFF 420
421 PPQLNSTVNETAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSG 480
481 LSLDSGHSPASLSSSEASSSSSSSSSSSSSSSSSSSSFSEEGAVGYSSDSENVDFEEAEG 540
541 AVGYQPEYSKFCRMSYQDPSQLHYLPYLEHVGHNHTYNMAPGTLDPEEPKLPSVGKKSSK 600
601 EKPSEFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRR 660
661 RGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKSKLLREKVEFLKSIRQMKQKVQNLYQE 720
721 VFGRLRDENGQPYSPNQYALQYASDGSVILIPRTLADQQARRQERKQKDRRK
Interface Residues: 660, 664, 665, 667, 668, 671, 672, 675
3D-footprint Homologues: 7x5e_E, 1skn_P, 4eot_A, 7x5e_F, 2wt7_A, 2wt7_B, 2dgc_A, 5t01_B, 5vpe_D
Binding Motifs: MA0089.1 sATGAC
Binding Sites: MA0089.1.1
MA0089.1.10
MA0089.1.11
MA0089.1.12
MA0089.1.13
MA0089.1.14
MA0089.1.15
MA0089.1.16
MA0089.1.17
MA0089.1.18
MA0089.1.19
MA0089.1.2
MA0089.1.20
MA0089.1.3
MA0089.1.4
MA0089.1.5
MA0089.1.6
MA0089.1.7
MA0089.1.8
MA0089.1.9
Publications: Johnsen O., Murphy P., Prydz H., Kolsto A.-B. Interaction of the CNC-bZIP factor TCF11/LCR-F1/Nrf1 with MafG: binding-site selection and regulation of transcription. Nucleic Acids Res. 26:512-520 (1998). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.