Transcription Factor

Accessions: P54842 (JASPAR 2024)
Names: Maf-B, MAFB_RAT, Transcription factor Maf-1, Transcription factor MafB, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B
Organisms: Rattus norvegicus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 323
Pfam Domains: 80-114 Maf N-terminal region
209-302 bZIP Maf transcription factor
Sequence:
(in bold interface residues)
1 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL 60
61 STPCSSVPSSPSFSPTEQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQP 120
121 LQSFDGFRSAHHHHHHHHPHPHHGYPGAGVTHDELGPHAHPHHHHHHQASPPPSSAASPA 180
181 QQLPTSHPGPGPHAAAAATAAGSNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLK 240
241 QKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEK 300
301 LANSGFREAGSTSDSPSSPEFFL
Interface Residues: 153, 244, 248, 249, 251, 252, 253, 255, 256
3D-footprint Homologues: 7mtl_A, 4eot_A, 7x5e_E, 7x5e_F, 2wt7_B, 5vpe_D, 1dh3_C, 6d6v_A
Binding Motifs: MA0117.1 GCTGAcks
Binding Sites: MA0117.1.1
MA0117.1.10
MA0117.1.11
MA0117.1.12
MA0117.1.13
MA0117.1.14
MA0117.1.15
MA0117.1.2
MA0117.1.3
MA0117.1.4
MA0117.1.5
MA0117.1.6
MA0117.1.7
MA0117.1.8
MA0117.1.9
Publications: Matsushima-Hibiya Y, Nishi S, Sakai M. Rat maf-related factors: the specificities of DNA binding and heterodimer formation. Biochemical and biophysical research communications 245:412-8 (1998). [Pubmed]
Related annotations: PaperBLAST

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