Transcription Factor
| Accessions: | KLF1_MOUSE (HOCOMOCO 10), P46099 (JASPAR 2024) |
| Names: | EKLF, Erythroid krueppel-like transcription factor, KLF1_MOUSE, Krueppel-like factor 1 |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 358 |
| Pfam Domains: | 275-299 C2H2-type zinc finger 275-299 Zinc finger, C2H2 type 291-313 Zinc-finger double domain 305-329 C2H2-type zinc finger 305-329 Zinc finger, C2H2 type 322-346 Zinc-finger double domain 335-357 C2H2-type zinc finger 335-357 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MASAETVLPSISTLTTLGQFLDTQEDFLKWWRSEETQDLGPGPPNPTGPSLHVSLKSEDP 60 61 SGEDDERDVTCAWDPDLFLTNFPGSESPGTSRTCALAPSVGPVAQFEPPESLGAYAGGPG 120 121 LVTGPLGSEEHTSWAHPTPRPPAPEPFVAPALAPGLAPKAQPSYSDSRAGSVGGFFPRAG 180 181 LAVPAAPGAPYGLLSGYPALYPAPQYQGHFQLFRGLAAPSAGGTAPPSFLNCLGPGTVAT 240 241 ELGATAIAGDAGLSPGTAPPKRSRRTLAPKRQAAHTCGHEGCGKSYSKSSHLKAHLRTHT 300 301 GEKPYACSWDGCDWRFARSDELTRHYRKHTGHRPFCCGLCPRAFSRSDHLALHMKRHL |
| Interface Residues: | 265, 269, 273, 287, 288, 289, 290, 291, 293, 294, 296, 297, 300, 317, 318, 319, 320, 321, 323, 324, 325, 328, 345, 346, 347, 348, 349, 350, 351, 352, 353, 356 |
| 3D-footprint Homologues: | 1ubd_C, 5kkq_D, 8ssq_A, 8ssu_A, 7w1m_H, 6jnm_A, 3uk3_C, 8cuc_F, 1tf3_A, 7y3l_A, 6ml4_A, 7n5w_A, 1tf6_A, 6u9q_A, 4x9j_A, 2i13_A, 1llm_D, 7ysf_A, 6wmi_A, 5ei9_F, 1mey_C, 7eyi_G, 5k5i_A, 2kmk_A, 2gli_A, 1g2f_F, 6blw_A, 8h9h_G, 5v3j_F, 2lt7_A, 7y3m_I, 6e94_A, 5und_A, 6a57_A, 2jpa_A, 4m9v_C, 5yel_A, 7txc_E, 5kl3_A, 2wbs_A, 5yj3_D, 2drp_D, 1f2i_J, 8gn3_A |
| Binding Motifs: | MA0493.1 rrCCACACCCw KLF1_MOUSE.H10MO.C|M01186 cwGGGTGkGGc |
| Binding Sites: | MA0493.1.1 MA0493.1.10 MA0493.1.11 MA0493.1.12 MA0493.1.13 MA0493.1.14 MA0493.1.15 MA0493.1.16 MA0493.1.17 MA0493.1.18 MA0493.1.19 MA0493.1.2 MA0493.1.20 MA0493.1.3 MA0493.1.4 MA0493.1.5 MA0493.1.6 MA0493.1.7 MA0493.1.8 MA0493.1.9 |
| Publications: | Miller I. J., Bieker J. J. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krueppel family of nuclear proteins. Mol. Cell. Biol. 13:2776-2786 (1993). [Pubmed] |
| Related annotations: | PaperBLAST |
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