Transcription Factor

						

			
Accessions: GATA3 (SMILE-seq 1.0)

			
Names: GATA-binding factor 3, GATA3, GATA3_HUMAN, Trans-acting T-cell-specific transcription factor GATA-3
Organisms: Homo sapiens
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: P23771
Notes: TF family: GATA
Length: 442
Pfam Domains:   263-296 GATA zinc finger
  317-349 GATA zinc finger
Sequence: 
(in bold interface residues)		   1 MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHV   60
  61 PPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKT  120
 121 SIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDE  180
 181 KECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVPEYSSGLFPPSSLL  240
 241 GGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPL  300
 301 IKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYELHNINRPLTMKKEG  360
 361 IQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTPT  420
 421 PMHPPSSLSFGPHHPSSMVTAM
Interface Residues: 107, 108, 272, 273, 275, 285, 289, 326, 327, 329, 339, 343, 344, 347, 363, 364, 366, 367
3D-footprint Homologues: 2fr4_L, 4hc9_A, 3vd6_C, 1gat_A, 3dfx_B, 4gat_A, 6cnb_R
Binding Motifs: GATA3 wGATAAsr
			
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.