Transcription Factor
| Accessions: | Q9Z0S2 (JASPAR 2024) |
| Names: | Homeobox protein LH-2, LHX2_MOUSE, LIM homeobox protein 2, LIM/homeobox protein Lhx2 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 406 |
| Pfam Domains: | 53-110 LIM domain 115-170 LIM domain 257-319 Homeobox KN domain 267-323 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKI 60 61 SDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHL 120 121 GISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAH 180 181 FNHADVAAAAAAAAAAKSAGLGSAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAY 240 241 NAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLA 300 301 QKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKTSDATLQTGTPSGPASELSNASLSP 360 361 SSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF |
| Interface Residues: | 266, 267, 268, 269, 270, 308, 309, 311, 312, 315, 316, 319, 320, 322, 323, 333, 336 |
| 3D-footprint Homologues: | 3d1n_M, 1puf_A, 5zfz_A, 2h1k_B, 6fqp_B, 1fjl_B, 3cmy_A, 1ig7_A, 6a8r_A, 1nk2_P, 6m3d_C, 1jgg_B, 3lnq_A, 2lkx_A, 2r5y_A, 1zq3_P, 6es3_K, 2ld5_A, 7q3o_C, 2hos_A, 5jlw_D, 4cyc_A, 2d5v_B, 4xrs_G, 3l1p_A, 7psx_B, 4j19_B, 3a01_E, 5flv_I, 1puf_B, 5zjt_E, 2hdd_A, 1b72_A, 5hod_A, 3rkq_B, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 1du0_A, 8g87_X, 4qtr_D, 1le8_B, 6fqq_E, 4xrm_B |
| Binding Motifs: | PH0092.1 waaayTAATTArykmhs |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.