Transcription Factor
| Accessions: | BATF3_DBD (HumanTF 1.0), BATF3 (HT-SELEX2 May2017) |
| Names: | 21 kDa small nuclear factor isolated from T-cells, B-ATF-3, Basic leucine zipper transcriptional factor ATF-like 3, BATF3, BATF3_HUMAN, Jun dimerization protein p21SNFT, ENSG00000123685 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, HT-SELEX2 May2017 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Uniprot: | Q9NR55 |
| Notes: | Ensembl ID: ENSG00000123685; DNA-binding domain sequence; TF family: bZIP; Clone source: Megaman, TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 112 |
| Pfam Domains: | 31-91 bZIP transcription factor 32-85 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 QGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKADK 60 61 LHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPV |
| Interface Residues: | 39, 40, 42, 43, 44, 46, 47, 48, 50, 51, 52, 54, 56 |
| 3D-footprint Homologues: | 4eot_A, 6mg1_B, 7x5e_F, 1skn_P, 1nwq_C, 5t2h_A, 5vpe_D, 1dh3_C, 5t01_B, 2c9l_Z |
| Binding Motifs: | BATF3_DBD TGATGACGTCATCr BATF3_2 grTGACGTCAyc BATF3_4 grTGACGTCAys BATF3_methyl_1 gaTGAyGTCAyc BATF3_methyl_3 grTGAyGTCAyc |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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