Transcription Factor

Accessions: 1a02_J (3D-footprint 20231221)
Names: Activator protein 1, AP-1 FRAGMENT JUN, AP1, JUN_HUMAN, p39, Proto-oncogene c-Jun, Transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P05412
Length: 52
Pfam Domains: 1-52 bZIP transcription factor
1-52 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 RKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQL
Interface Residues: 2, 3, 5, 6, 7, 9, 10, 13, 14
3D-footprint Homologues: 7x5e_F, 1gd2_G, 1nwq_C, 2dgc_A, 1dh3_C, 5t01_B, 5vpe_D
Binding Motifs: 1a02_FJN GGAananwTGnyTCA
Publications: Chen L., Glover J. N. M., Hogan P. G., Rao A., Harrison S. C. Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.. Nature 392:42-48 (1998). [Pubmed]
Related annotations: PaperBLAST

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