Transcription Factor

						

			
Accessions: T018410_1.02 (CISBP 1.02)

			
Names: hlh-30, T018410_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 361
Pfam Domains:   102-154 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MGMEDDQRMRPGATRPMTIGGEKTMSMARPIPGASSRAGSGHSGSPITIPNAMSNNFRQV   60
  61 VSSSAPTSSIDIEKMIGAVSNGGGNSGGDNDPEDYYRDRRKKDIHNMIERRRRYNINDRI  120
 121 KELGQMLPKNTSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADR  180
 181 VKELEEMLARQGVQVPPSHLPPIPKVIERPIKQEIDESPPNHTPTGSFVSSSGFLSEVTN  240
 241 NTAAMQITSPNDSRPNNFMNNSAPSDSFFSVGSASPPDYRTSSGTASWKLPGSNAFSDLM  300
 301 MDDLNPMMNGDPLISSAGAHPSPHFHSSQMSPDIHWDASGFSPDPINTQQSNSGHYHMDF  360
 361 S
Interface Residues: 102, 104, 105, 106, 108, 109, 110, 112, 113, 137, 139, 141, 144, 145, 146, 149, 193
3D-footprint Homologues: 1a0a_B, 1an4_A, 7d8t_A, 5i50_B, 7xi3_A, 4zpk_A, 1am9_A, 7f2f_B, 5nj8_D, 3mva_O, 6g1l_A, 5eyo_A, 7ssa_L, 4h10_A, 8osl_O, 6od3_F, 5gnj_I, 5v0l_A, 4h10_B, 8osl_P, 2ypa_B, 2ypa_A, 7xhv_B, 5v0l_B, 7xi3_B, 5t2n_A
Binding Motifs: M0240_1.02 TCACGTGw
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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