Transcription Factor
| Accessions: | P10105 (JASPAR 2024) |
| Names: | F24, F90-2, Homeotic protein labial, LAB_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P10105 |
| Length: | 635 |
| Pfam Domains: | 510-564 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MMDVSSMYGNHPHHHHPHANAYDGYSTTTASAANASSYFAPQQHQPHLQLQQQQQHQHLQ 60 61 QPQQHLTYNGYESSSPGNYYPQQQAQLTPPPTSSHQVVQQHQQQQQAQQQQLYPHSHLFS 120 121 PSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPIT 180 181 AANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLH 240 241 ASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGN 300 301 LANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPG 360 361 SSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPSYLPAPKLPASGI 420 421 ASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAG 480 481 SAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEI 540 541 ANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPELQ 600 601 LKSQGSDLGGNELATGAPSTPTTAMTLTAPTSKQS |
| Interface Residues: | 508, 509, 510, 511, 549, 550, 552, 553, 556, 557, 560, 561, 564 |
| 3D-footprint Homologues: | 2h1k_B, 1puf_A, 1nk2_P, 6es3_K, 7q3o_C, 1puf_B, 1jgg_B, 4xrs_G, 3d1n_M, 2hos_A, 5zfz_A, 4cyc_A, 6m3d_C, 1au7_A, 5flv_I, 3l1p_A, 2ld5_A, 1fjl_B, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 1b72_A, 5hod_A, 3lnq_A, 2lkx_A, 1ig7_A, 6a8r_A, 3cmy_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1zq3_P, 1k61_B, 1o4x_A, 8g87_X, 4qtr_D, 1mnm_C, 1du0_A |
| Binding Motifs: | MA0230.1 TTAATkA |
| Binding Sites: | MA0230.1.2 MA0230.1.6 MA0230.1.8 MA0230.1.1 MA0230.1.7 MA0230.1.18 MA0230.1.14 MA0230.1.20 MA0230.1.4 MA0230.1.3 MA0230.1.10 MA0230.1.12 MA0230.1.16 MA0230.1.11 MA0230.1.13 MA0230.1.15 MA0230.1.17 MA0230.1.19 MA0230.1.5 MA0230.1.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.