Transcription Factor

Accessions: P70321 (JASPAR 2024)
Names: HXB13_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P70321
Length: 286
Pfam Domains: 21-124 Hox protein A13 N terminal
219-275 Homeobox domain
Sequence:
(in bold interface residues)
1 MEPGNYATLDGAKDIEGLLGAGGGRNLVSHSSPLASHPAAPTLMPTVNYAPLDLPGSAEP 60
61 PKQCHPCPGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQTAALATYPSETPAPGEE 120
121 YPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQPWALAGGWN 180
181 SQMCCQGEQNPPGPFWKAAFAEPSVQHPPPDGCAFRRGRKKRIPYSKGQLRELEREYAAN 240
241 KFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSTTP
Interface Residues: 48, 217, 219, 220, 221, 222, 260, 261, 263, 264, 267, 268, 271, 272, 275
3D-footprint Homologues: 6sei_C, 6fqp_B, 1ig7_A, 2h1k_B, 1puf_A, 3cmy_A, 6a8r_A, 1fjl_B, 5zfz_A, 2lkx_A, 1jgg_B, 3lnq_A, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 5flv_I, 3a01_E, 7psx_B, 5zjt_E, 4cyc_A, 2hdd_A, 2r5y_A, 1puf_B, 6m3d_C, 5jlw_D, 2hos_A, 4xrs_G, 1b72_A, 3rkq_B, 1e3o_C, 1au7_A, 7xrc_C, 2xsd_C, 1le8_A, 1o4x_A, 1le8_B, 1du0_A, 6fqq_E, 5hod_A, 1mnm_C, 4qtr_D, 1k61_B
Binding Motifs: PH0057.1 mrmCyAATAAAAwwys
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.