Transcription Factor

Accessions: 1am9_D (3D-footprint 20231221)
Names: bHLHd1, Class D basic helix-loop-helix protein 1, SRBP1_HUMAN, SREBP-1, STEROL REGULATORY ELEMENT BINDING PROTEIN 1A, Sterol regulatory element-binding protein 1, Sterol regulatory element-binding transcription factor 1, Transcription factor SREBF1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P36956
Length: 76
Pfam Domains: 6-56 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 QSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQ 60
61 KLKQENLSLRTAVHKS
Interface Residues: 7, 9, 10, 11, 13, 14, 17, 18, 39, 41, 74, 75, 76
3D-footprint Homologues: 2ypa_A, 7z5k_B, 1an4_A, 5v0l_A, 4h10_A, 7rcu_E, 5i50_B, 8osl_O, 6g1l_A, 4h10_B, 7ssa_L, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D, 7f2f_B, 5eyo_A, 1am9_A, 8osl_P, 5nj8_C, 2yvh_A
Binding Motifs: 1am9_CD GTGGGGTGAC
Binding Sites: 1am9_E
1am9_H
Publications: Párraga A, Bellsolell L, Ferré-D'Amaré A.R, Burley S.K. Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution. Structure (London, England : 1993) 6:661-72 (1998). [Pubmed]
Related annotations: PaperBLAST

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